Treatment of Arthritis, Dysmenorrhoea, and Pyrexia Using Brufen Tablets

What is Primary Dysmenorrhea?

Dysmenorrhea can include different kinds of pain, including sharp, throbbing, dull, nauseating, burning, or shooting pain. Dysmenorrhea may precede menstruation by several days or may accompany it, and it usually subsides as menstruation tapers off. Dysmenorrhea may coexist with excessively heavy blood loss, known as menorrhagia.
Primary dysmenorrhea is menstrual pain that's not a symptom of an underlying gynecologic disorder but is related to the normal process of menstruation. It often begins with the onset of ovulatory cycles six months to one year after the first menstrual cycle. The pain begins with the onset of the period and may last for 24-72 hours.
Primary dysmenorrhea is more likely to affect girls during adolescence. Fortunately for many women, the problem eases as they mature, particularly after a pregnancy. Although it may be painful and sometimes debilitating for brief periods of time, it is not harmful.

What is Pyrexia?

Fever, also known as Pyrexia is one of the most common medical signs and is characterized by an elevation of body temperature above the normal range of 36.5-37.5°C (97.7-99.5 °F) due to an increase in the temperature regulatory set-point. As a person's temperature increases, there is, in general, a feeling of cold despite an increase in body temperature.
With the exception of very high temperatures, treatment to reduce fever is often not necessary; however, antipyretic medications can be effective at lowering the temperature, which may improve the affected person's comfort.

Brufen Tablets – Product Information

Brufen Tablets (Ibuprofen) is used for relief of the signs and symptoms of Rheumatoid arthritis, Osteoarthritis, Juvenile rheumatoid arthritis, Primary dysmenorrhoea, and Pyrexia. Brufen is also used for the relief of acute and/or chronic pain states in which there is an inflammatory component.
The active ingredient present in Brufen Tablets is Ibuprofen.
Ibuprofen is marketed under trade names such as Motrin, Brufen, Ibugesic, Advil, Nuprin, Calprofen, Ribafen, Nurofen.

Brufen Tablets - Contraindications

Brufen Tablets is contraindicated for patients with hypersensitivity to Ibuprofen or any of the inactive ingredients present in Brufen tablets.
Hypersensitivity (e.g. asthma, rhinitis or urticaria) to aspirin or other nonsteroidal anti-inflammatory drugs. Ibuprofen should not be used in active gastrointestinal bleeding or perforation related to previous NSAID therapy. Ibuprofen should not be used in patients with active, or a history of, ulcerative colitis, Crohn's disease, recurrent peptic ulceration or gastrointestinal haemorrhage.

Brufen Tablets - Dosage

Brufen Tablets comes as an oral tablet in 200 mg, 400 mg and 600 mg dosage forms. The recommended adult Oral dosage of Brufen Tablets for adults is given below:
Recommended Adult Dosage:
The recommended initial dosage of Brufen tablets is 1200 mg to 1800 mg daily in divided doses. Some patients can be maintained on 600 to 1200 mg daily. In severe or acute conditions it can be advantageous to increase the dosage until the acute phase is brought under control, providing that the total daily dosage does not exceed 2400mg in divided doses.
Primary Dysmenorrhoea:
For the treatment of dysmenorrhea, beginning with the earliest onset of such pain or menstrual bleeding, Ibuprofen tablets should be given in a dose of 400 mg every 4 to 6 hours as necessary with amaximum total daily dose of 1,600 mg.
Mild to Moderate Pain:
The recommended adult dosage is 400 mg every 4 to 6 hours as necessary for relief of pain.
Maintenance Dose:
In all indications the doses should be adjusted for each patient and the smallest dose that results in acceptable control of the symptoms employed. In general, patients with rheumatoid arthritis and osteo arthritis tend to require higher doses than patients with other conditions.

Side Effects of Brufen Tablets

The common possible side effects reported in patients treated with Brufen Tablets include Nausea, epigastric pain, heartburn, diarrhea, abdominal distress, nausea and vomiting, indigestion, constipation, abdominal cramps or pain, fullness of GI tract (bloating and flatulence),Dizziness, headache, nervousness, Rash (including maculopapular type), pruritus, Tinnitus, decreased appetite, Edema, and fluid retention.
Rare side effects include Gastic or duodenal ulcer with bleeding and/or perforation, gastrointestinal hemorrhage, melena, gastritis, hepatitis, jaundice, abnormal liver function tests; pancreatitis, Depression, insomina, confusion, emotional lability, somnolence, aseptic meningitis with fever and coma, vesiculobullous eruptions, urticaria, erythema multiforme, Stevens-Johnson syndrome, alopecia,hearing loss, amblyopia (blurred and/or diminished vision, scotomata and/or changes in color vision), neutropenia, agranulocytosis, aplastic anemia, hemolytic anemia (sometimes Coombs Positive), thrombocytopenia with or without purpura, eosinophilia, decreases in hemoglobin and hematocrit, congestive heart failure in patients with marginal cardiac function, elevated blood pressure, palpitations, Syndrome of abdominal pain, fever, chills, nausea and vomiting; anaphylaxis; bronchospasm, acute renal failure, decreased creatinine clearance, polyuria, azotemia, cystitis, hematuria, dry eyes and mouth, gingival ulcer and rhinitis.

Brufen Tablets - More Details

For more details on Brufen Tablets please read the Prescription Information or watch the presentation below:

Brufen Tablets for Treatment of Arthritis, Dysmenorrhoea, and Pyrexia

Treatment of High Cholesterol Using Crestor Tablets

What is High Cholesterol?

Cholesterol is a lipid (fat) which is produced by the liver and is vital for normal body function. Every cell in our body has cholesterol in its outer layer. The desirable levels of Cholesterol is less than 200 mg/dL, borderline high value is 200 to 239 mg/dL and a high value is 240 mg/dL and above.
Hypercholesterolemia is the presence of high levels of cholesterol in the blood.
Cholesterol can build up in the artery wall, restricting the flow of blood to your heart, brain and the rest of your body. High cholesterol levels can cause:
1)Atherosclerosis which means narrowing of the arteries
2)Higher coronary heart disease risk - an abnormality of the arteries that supply blood and oxygen to the heart.
3)Heart attack occurs when the supply of blood and oxygen to an area of heart muscle is blocked, usually by a clot in a coronary artery. This causes your heart muscle to die.
4)Angina (chest pain or discomfort) occurs when your heart muscle does not get enough blood.
5)Other cardiovascular conditions - diseases of the heart and blood vessels.
6)Stroke and mini-stroke
It also increases the chance of a blood clot

Crestor Tablets (Rosuvastatin Calcium) – Product Information

Crestor Tablets manufactured by Astra Zeneca is a medicine used in combination with exercise, diet, and weight-loss to treat high cholesterol and related conditions. Crestor is used when the the response to diet and exercise is not adequate.
It is also indicated for risk reduction of MI, stroke, and arterial revascularization procedures in patients without clinically evident CHD, but with multiple risk factors.
Crestor belongs to a group of medicines known as 'statins'. It lowers the "bad" cholesterol, and raises the "good" cholesterol when exercise and changes to diet are not enough on their own. It also lowers the risk of heart attacks and strokes.
The active ingredient present in Crestor Tablets is Rosuvastatin Calcium.

Crestor Tablets (Rosuvastatin calcium) - Contraindications

Crestor Tablets (Rosuvastatin calcium) is contraindicated in patients with

• Hypersensitivity to Rosuvastatin calcium or any component of this product.
• Pregnancy
• Active liver disease or persistent, unexplained elevations in transaminases.
• During pregnancy, while breast-feeding and in women of child-bearing potential not using appropriate contraceptive measures.
• Pre-disposing factors for myopathy/rhabdomyolysis.Such factors include:
  • hypothyroidism
  • personal or family history of hereditary muscular disorders
  • previous history of muscular toxicity with another HMG-CoA reductase inhibitor or fibrate
  • alcohol abuse
  • situations where an increase in rosuvastatin plasma levels may occur
  • severe renal impairment (CrCl < 30 mL/min)
  • Asian patients
  • concomitant use of fibrates

Crestor Tablets (Rosuvastatin calcium) - Dosage

Crestor Tablets may be given at any time of the day, with or without food.The recommended adult Oral dosage of various indications is given below:
Prevention Of Major Cardiovascular Events:
A dose of 20 mg once daily has been found to reduce the risk of major cardiovascular events.
Hypercholesterolaemia:
The usual dose range is 10 - 40 mg orally once a day. The dosage of Crestor should be individualised according to the goal of therapy and patient response. The majority of patients are controlled at the start dose.
Primary hypercholesterolaemia, mixed dyslipidaemia and isolated hypertriglyceridaemia:
The usual start dose is 10 mg once a day. For patients with severe hypercholesterolaemia, a start dose of 20 mg may be considered.
Homozygous familial hypercholesterolaemia:
For patients with homozygous familial hypercholesterolaemia a start dose of 20 mg once a day is recommended.
Dosage In Patients With Renal Insufficiency
The usual dose range applies in patients with mild to moderate renal impairment.For patients with severe renal impairment the dose of Crestor should not exceed 10 mg once daily.
Race
A 5 mg starting dose of Crestor should be considered for Asian patients.

Side Effects of Crestor Tablets (Rosuvastatin Calcium)

Crestor (Rosuvastatin calcium) is generally well tolerated. The side effects seen with Crestor are generally mild and transient. In controlled clinical trials, less than 4% of CRESTOR treated patients were withdrawn due to adverse events. This withdrawal rate was comparable to that reported in patients receiving placebo.
Inform your doctor if you notice any of the following side effects and they worry you Headache, myalgia, asthenia, stiff or painful joints (arthralgia), constipation, dizziness, nausea(feeling sick), unusual tiredness, memory loss, skin rash, itching or hives, stomach pain.
Tell your doctor immediately or go to Accident and Emergency at your nearest hospital in case you notice any of the following serious side effects:
muscle pain, aching muscles, muscle tenderness or weakness not caused by exercise, particularly if you also have a fever or generally feel unwell,swelling of the face, eyelids and lips.
You may need urgent medical attention. Serious side effects of Crestor Tablets are rare.

Crestor Tablets (Rosuvastatin calcium) - More Details

For more details please read the Prescription Information or watch the presentation below:

Crestor Tablets to treat high cholesterol and related conditions

Cholesterol Reduction by Using Generic Lipitor Tabets

Generic Lipitor (Atorlip Tablets) – Product Information

The active ingredient present in Atorlip Tablets is Atorvastatin Calcium .
Generic Lipitor tablets can lower the risk for heart attack, stroke, certain types of heart surgery, and chest pain in patients who have heart disease or risk factors for heart disease such as age, smoking, high blood pressure, low HDL, or family history of early heart disease. Generic Lipitor (Atorvastatin Calcium) tablets can also lower the risk for heart attack or stroke in patients with diabetes and risk factors such as diabetic eye or kidney problems, smoking, or high blood pressure.
Generic Lipitor is also available as Atoris, Lipvas, Sortis, Torvast, Torvacard, Tortalip and Tulip. Atorlip Tablets are available in strengths of 5 mg, 10 mg , 20 mg and 40 mg. Each film-coated tablet contains Atorvastatin calcium equivalent to Atorvastatin 5 mg, 10 mg , 20 mg, 40 mg respectively.

Uses Of Generic Lipitor Tablets

Generic Lipitor (Atorlip Tablets) are indicated along with diet changes to reduce the amount of cholesterol and certain fatty substances in blood. This reduces or prevents Cardiovascular Diseases. In particular Atorlip tablets reduce the risk of myocardial infarction, stroke, revascularization procedures, and angina. Drug therapy is recommended as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other non-pharmacologic measures alone has proved to be inadequate.

Generic Lipitor (Atorlip Tablets) - Dosage And Administration

The recommended starting dose of Generic Lipitor (Atorlip Tablets) in adult patients is 10 or 20 mg once daily. Patients that require large Low-Density-Lipoprotein cholesterol (LDL-C) reduction (>45%) can start at 40 mg once daily. The recommended starting dose for pediatric patients is 10 mg once daily; maximum recommended dose: 20 mg once daily.

Atorlip Tablets (Generic Lipitor)- Contraindications

The use of Generic Lipitor is contraindicated in patiennts that have a hypersensitivity to Atorvastatin calcium or any other component of this medication. Generic Lipitor (Atorlip Tablets) are also contraindicated in persons with Active liver disease, Women who are pregnant or may become pregnant and Nursing mothers.

Warnings And Precautions

Skeletal muscle effects:
Risks increase when higher doses are used concomitantly with cyclosporine, fibrates, and strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, HIV protease inhibitors). Predisposing factors include advanced age (> 65), uncontrolled hypothyroidism, and renal impairment. Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported. In cases of myopathy or rhabdomyolysis, therapy should be temporarily withheld or discontinued.
Liver enzyme abnormalities and monitoring:
Persistent elevations in hepatic transaminases can occur. Monitor liver enzymes before and during treatment. A higher incidence of hemorrhagic stroke was seen in patients without CHD but with stroke or TIA within the previous 6 months in the Lipitor 80 mg group vs. placebo.

Generic Lipitor Tablets (Atorlip) Side Effects

The most commonly reported side effects in patients undergoing treatment with Generic Lipitor tablets with an incidence rate of 2% or more were: nasopharyngitis, arthralgia, diarrhea, pain in extremity, and urinary tract infection.

Generic Lipitor (Atorvastatin Calcium Tablets) - More Details

For more details on Generic Lipitor (Atorlip tablets) please read the Prescribing Information or watch the presentation below:

Reduce Cholesterol With Generic Lipitor

Treatment of Epileptic Seizures and Trigeminal Neuralgia using Generic Tegretol Tablets

What is an Epileptic Seizure?

An Epileptic Seizure (also known as a fit or Seizure) is a transient symptom of "abnormal excessive or synchronous neuronal activity in the brain". Seizures are generally described in two major groups of seizures, primary generalized seizures and partial seizures. The difference between these types is in how and where they begin.
Epileptic Seizures can manifest as an alteration in mental state, tonic or clonic movements, convulsions, and various other psychic symptoms. Sometimes it is not accompanied by convulsions but a full body "slump", where the person simply will lose body control and slump to the ground.

Generic Tegretol (Zeptol Tablets) – Product Information

Generic Tegretol Tablets (Zeptol Tablets) is used for controlling Partial seizures with complex symptomatology, Generalized tonic-clonic seizures (grand mal) and Mixed seizure patterns which include the above, or other partial or generalized seizures. Generic Tegretol is also used in the treatment of the pain associated with true trigeminal neuralgia as well as glossopharyngeal neuralgia.
The active ingredient present in Generic Tegretol is Carbamazepine.
Carbamazepine is available as Biston, Calepsin, Carbatrol, Epitol, Equetro, Finlepsin, Sirtal, Stazepine, Telesmin, Tegretol, EPITAB XR, Teril, Timonil, Trimonil, Epimaz, Carbama/Carbamaze, Amizepin, Carzine, Mazetol, Tegrital, Tegrita, Zeptol, Karbapin, Hermolepsin, Degranol, and Tegretal.

Generic Tegretol (Zeptol Tablets) - Contraindications

Generic is contraindicated in patients with

• Hypersensitivity to Carbamazepine or any inactive component present in Generic Tegretol
• Known sensitivity to any of the tricyclic compounds, such as amitriptyline, desipramine, imipramine, protriptyline, nortriptyline, etc.
• History of previous bone marrow depression
• Use with monoamine oxidase inhibitors is not recommended
• MAO inhibitors should be discontinued for a minimum of 14 days, or longer
• Coadministration of carbamazepine with nefazodone is contraindicated.

Generic Tegretol - Dosage

The recommended adult Oral dosage of Generic Tegretol (Zeptol Tablets) for adults is given below:
Epilepsy
Adults and children over 12 years of age:
Initial: 200 mg twice a day.Increase at weekly intervals by adding up to 200 mg/day using a twice a day regimen until the optimal response is obtained. Dosage generally should not exceed 1000 mg daily in children 12-15 years of age, and 1200 mg daily in patients above 15 years of age.
Maintenance: Adjust dosage to the minimum effective level, usually 800-1200 mg daily.
Trigeminal Neuralgia
Adult Dosage:
Initial: On the first day, 100 mg twice a day for a total daily dose of 200 mg. This daily dose may be increased by up to 200 mg/day using increments of 100 mg every 12 hours, only as needed to achieve freedom from pain. Do not exceed 1200 mg daily.
Maintenance: Control of pain can be maintained in most patients with 400-800 mg daily. However, some patients may be maintained on as little as 200 mg daily, while others may require as much as 1200 mg daily.

Side Effects of Generic Tegretol (Zeptol Tablets)

The side effects reported in patients treated with Generic Tegretol are dizziness, drowsiness, unsteadiness, headache, ataxia, fatigue, diplopia, leukopenia, oedema, fluid retention, weight increase, hyponatraemia and blood osmolarity decreased, nausea, vomiting , and allergic skin reactions (dermatitis allergic, urticaria)

Generic Tegretol (Zeptol Tablets) - More Details

For more details please read the Prescription Information or watch the presentation below:

Generic Tegretol Tablets for treatment of Epileptic Seizures and Trigeminal Neuralgia

Treatment of Multiple Actinic or Solar Keratoses Using Generic Carac Cream

Generic Carac Cream (Flonida Cream) – Product Information

Generic Carac cream (Flonida Cream) is used for the topical treatment of multiple actinic or solar keratoses of the face and anterior scalp. It is also used to treat other conditions such as basal cell carcinomas of the skin, Bowen's disease (a type of skin cancer), psoriasis, genital warts and porokeratosis (an unusual inherited skin condition causing dry patches on the arms and legs).
The active ingredient present in Generic Carac cream is Fluorouracil.
Fluorouracil cream is marketed under trade names such as Carac, Flonida, Fluorouracil Topical, 5-Fluorouracil, 5-FU, Efudex, Fluoroplex and under various other brand names. Generic Carac® Cream, (Flonida cream 1% & Flonida Cream 5%) , contains Fluorouracil for topical dermatologic use.

Dosage And Administration

Generic Carac cream (Flonida cream) comes in 1% and 5% dosage forms in a 10 grams tube. Generic Carac cream should be applied twice daily with fingertips and hands should be washed thouroughly after application. The usual duration of treatment for an initial course of therapy is three to four weeks, but this may be prolonged. Lesions on the face usually respond more quickly than those on the trunk or lower limbs whilst lesions on the hands and forearms respond more slowly.
Healing may not be complete until one or two months after therapy is stopped. The recommended dosage of Generic Carac cream is given below:
Dosage for Treatment of Pre-malignant Conditions in Adults
The cream should be applied thinly to the affected area once or twice daily. an occlusive dressing is not essential.
Dosage for Treatment of Malignant Conditions in Adults
The cream should be applied once or twice daily under an occlusive dressing where this is practicable.The cream should not harm healthy skin. Treatment should be continued until there is marked inflammatory response from the treated area, preferably with some erosion in the case of pre-malignant conditions. Severe discomfort may be alleviated by the use of topical steroid cream.

Generic Carac Cream Tablets - Contraindications

Generic Carac Cream is contraindicated in patients with known hypersensitivity to Fluorouracil or to any component present in Generic Carac (Flonida cream).
Fluorouracil may cause fetal harm when administered to a pregnant woman. Fluorouracil is contraindicated in women who are or may become pregnant. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus.
Generic Carac should not be used in patients with dihydropyrimidine dehydrogenase (DPD) enzyme deficiency.

Side Effects of Generic Carac Cream Tablets

The common side effects reported in patients treated with Generic Fluorouracil cream (Flonida cream) include pain, pruritus, burning, irritation, inflammation, allergic contact dermatitis and telangiectasia have been reported. Occasionally, hyperpigmentation and scarring have also been reported.

More Details on Generic Fluorouracil cream

For more details on Generic Carac (Generic Fluorouracil cream) please read the Prescribing Information or watch the the presentation below.

Fluorouracil Cream for Treatment of Keratoses & Skin Lesions

Treatment of Major Depressive Disorder and Generalized Anxiety Disorder using Generic Lexapro Tablets

What is Major Depressive Disorder (MDD)?

Major depressive disorder is a disabling condition which is thought to be caused by a chemical imbalance in parts of the brain. This imbalance affects the whole body and can cause emotional and physical symptoms such as feeling low in spirit, loss of interest in activities, being unable to enjoy life, poor appetite or overeating, disturbed sleep, often waking up early, loss of sex drive, lack of energy and feeling guilty over nothing.
True clinical depression is a mood disorder in which feelings of sadness, loss, anger, or frustration interfere with everyday life for weeks or longer and adversely affects a person's family, work or school life, sleeping and eating habits, and general health.
Generic Lexapro corrects this chemical imbalance and may help relieve the symptoms of depression. Generic Lexapro may also be used to treat patients who have excessive anxiety and worry.

What is Generalized Anxiety Disorder (GAD)?

Generalized anxiety disorder (GAD) is an anxiety disorder that is characterized by excessive, uncontrollable and often irrational worry about everyday things that is disproportionate to the actual source of worry.
People with Generalized Anxiety Disorder (GAD) are extremely worried about these and many other things, even when there is little or no reason to worry about them. For diagnosis of GAD, symptoms must last at least 6 months.
This excessive worry often interferes with daily functioning, as individuals suffering GAD typically anticipate disaster, and are overly concerned about everyday matters such as health issues, money, death, family problems, friendship problems, interpersonal relationship problems, or work difficulties.
Physical symptoms that individuals affected with GAD exhibit include fatigue, fidgeting, headaches, muscle tension, muscle aches, difficulty swallowing, bouts of difficulty breathing, trembling, twitching, irritability, sweating, nausea, numbness in hands and feet, lightheadedness, having to go to the bathroom frequently, feeling out of breath, restlessness, insomnia, hot flashes and rashes and inability to fully control the anxiety.

Generic Lexapro (S Citadep Tablets) – Product Information

Generic Lexapro Tablets (S Citadep) is used for acute as well as maintenance treatment of Major Depressive Disorder (MDD) in adults and adolescents aged between 12 to 17 years of age. It is also used for acute treatment of Generalized Anxiety Disorder (GAD). Escitalopram Oxalate tablets are sometimes prescribed off-label for the treatment of other indications like social anxiety disorder, panic disorder and obsessive-compulsive disorder.
The active ingredient present in Generic Lexapro is Escitalopram Oxalate.
Escitalopram Oxalate is available as Nexito, Anxiset-E, Exodus, Esto, Lexapro, Cipralex, S Citadep, Seroplex, Elicea, Lexamil, Lexam, Entact, Losita, Reposil, Animaxen, Esitalo, Lexamil.

Generic Lexapro (S Citadep Tablets) - Contraindications

Generic Lexapro (S Citadep Tablets) is contraindicated in patients with

• A known hypersensitivity to Escitalopram Oxalate or citalopram or to any component of this medication
• Serotonin Syndrome and MAOIs: Do not use MAOIs intended to treat psychiatric disorders with Lexapro or within 14 days of stopping treatment with Lexapro. Do not use Lexapro within 14 days of stopping an MAOI intended to treat psychiatric disorders. In addition, do not start Lexapro in a patient who is being treated with linezolid or intravenous methylene blue.
• Pimozide: Do not use concomitantly

Generic Lexapro (S Citadep Tablets) - Dosage

The dosage of Generic Lexapro (S Citadep Tablets) for various indications is given below:
Major Depressive Disorder (MDD):
Adolescents and Adults: The recommended starting dose is 10 mg once daily and the maximum dosage should not exceed 20 mg once daily
Generalized Anxiety Disorder (GAD):
Adults Dosage: The recommended starting dose is 10 mg once daily.

Side Effects of Generic Lexapro Tablets (S Citadep)

The most common side effects reported in patients treated with Generic Lexapro Tablets (Escitalopram Oxalate) with an incidence of 5% or more and at least twice the incidence of placebo patients are: insomnia, ejaculation disorder (primarily ejaculatory delay), nausea, sweating increased, fatigue and somnolence, decreased libido, and anorgasmia.

Generic Lexapro (Escitalopram Oxalate Tablets) - More Details

For more details on Generic Lexapro please read the Prescribing Information or watch the presentation below:

Generic Lexapro Tablets for Treatment of Major Depressive Disorder and Generalized Anxiety Disorder

Treatment of Shingles, Genital Herpes and Cold Sores using Generic Famvir Tablets

What are Shingles (Herpes Zoster)?

Shingles (herpes zoster) is a disease caused by the varicella-zoster virus - the same virus that causes chickenpox. After you have chickenpox, the virus stays in your body. It may not cause problems for many years. As you get older, the virus may reappear as shingles. Unlike chickenpox, you can't catch shingles from someone who has it.
The earliest symptoms of herpes zoster, which include headache, fever, and malaise, are nonspecific, and may result in an incorrect diagnosis. These symptoms are commonly followed by sensations of burning pain, itching, hyperesthesia (oversensitivity), or paresthesia ("pins and needles": tingling, pricking, or numbness). The pain may be mild to extreme in the affected dermatome, with sensations that are often described as stinging, tingling, aching, numbing or throbbing, and can be interspersed with quick stabs of agonizing pain.

What are Genital Herpes?

Genital Herpes is a common infection caused by the herpes simplex virus (HSV). It causes painful blisters on the genitals and the surrounding areas. As genital herpes can be passed to others through intimate sexual contact, it is often referred to as a sexually transmitted infection (STI).
You are most likely to get herpes if you touch the skin of someone who has herpes sores, blisters, or a rash. However, the herpes virus can still be spread even when no sores or other symptoms are present. Sometimes, the person does not even know they are infected.

What are Cold Sores?

Cold sores (Herpes labialis, or orolabial herpes) are small blisters that develop on the lips or around the mouth due to infection of the lip by herpes simplex virus (HSV-1).
They are caused by the herpes simplex virus and usually clear up without treatment within 7-10 days. Cold sores often start with a tingling, itching or burning sensation around your mouth. An outbreak typically causes small blisters or fluid-filled sores to appear, on or around the mouth, most commonly on the edges of your lower lip. The sores typically heal within 2-3 weeks, but the herpes virus remains dormant in the facial nerves, following orofacial infection, periodically reactivating (in symptomatic people) to create sores in the same area of the mouth or face at the site of the original infection.

Generic Famvir (Virovir Tablets) – Product Information

Generic Famvir Tablets (Virovir) is used for the treatment of herpes zoster (shingles), acute treatment of first episode and recurrences of genital herpes infections, and for the suppression of recurrent genital herpes. Generic Famvir is also used for the treatment of recurrent herpes labialis (cold sores). Generic Famvir (Virovir Tablets) is also used to treat immunocompromised patients with herpes zoster or herpes simplex infections.
The active ingredient present in Generic Famvir is Famciclovir.
Famciclovir is available as Famvir, Virovir, and other generic brands.

Generic Famvir (Virovir Tablets) - Contraindications

Generic Famvir (Virovir Tablets) is contraindicated in patients with

• Known hypersensitivity to Famciclovir or other constituents of Generic Famvir.
• Hypersensitivity to Penciclovir, the active metabolite of Famciclovir.

Generic Famvir (Virovir Tablets) - Dosage

Herpes Zoster Infections In Immunocompetent Adults
250 mg three times a day or 500 mg twice a day or 750 mg once a day for seven days for the treatment of the acute phase of herpes zoster. 500 mg three times a day for seven days for the treatment of ophthalmic zoster. Treatment yields better results if initiated as soon as possible after rash onset. For those at risk of Post-herpetic neuralgia (PHN), 250-500 mg three times a day for seven days, taken during the acute phase of the disease, to decrease the duration and incidence of PHN.
Herpes Zoster Infections In Immunocompromised Adults
500 mg three times daily for ten days. Initiation of treatment is recommended as soon as possible after rash onset.
Herpes Simplex Infections In Immunocompetent Adults
First episode of genital herpes
250 mg three times daily for five days. Initiation of treatment is recommended as soon as possible after onset of lesions.
Recurrent genital herpes
1000 mg twice daily for one day or 125 mg twice daily for five days. Initiation of treatment is recommended during the prodromal period or as soon as possible after onset of lesions.
Recurrent Herpes Labialis (Cold Sores)
1500 mg as a single dose for one day. Initiation of treatment is recommended at the earliest sign or symptom of a cold sore (e.g. tingling, itching or burning)
Herpes Simplex Infections In Immunocompromised Adults
500 mg twice daily for seven days. Initiation of treatment is recommended as soon as possible after rash onset.
Suppression Of Recurrent Genital Herpes Infections
250 mg twice daily. The length of treatment depends on the severity of the disease. Therapy should be re-evaluated after 12 months in order to observe possible changes in the natural history of the disease. A dose of 500 mg twice a day has been shown to be efficacious in HIV patients.

Side Effects of Generic Famvir Tablets

The most common side effects reported in patients treated with Generic Famvir include Headache,Dizziness,Vomiting, nausea, Abnormal liver function tests, Rash, pruritus. Uncommon side effects include Confusion (predominantly in the elderly), Somnolence (predominantly in the elderly), Angioedema (e.g. face edema, eyelid edema, periorbital edema, pharyngeal edema) and urticaria. Rare side effects include Thrombocytopenia, Hallucinations and Cholestatic jaundice. Cases of serious skin reactions such as erythema multiforme, Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis have been reported from post-marketing experience with Famvir Tablets (Famciclovir) via spontaneous case reports.

- More Details

For more details please read the Prescription Information or watch the presentation below:

Treatment of Hypertension using Generic Bystolic Tablets

What is hypertension?

Hypertension or high blood pressure, sometimes called arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is elevated. This requires the heart to work harder than normal to circulate blood through the blood vessels. Blood pressure is summarised by two measurements, systolic and diastolic, which depend on whether the heart muscle is contracting (systole) or relaxed between beats (diastole) and equate to a maximum and minimum pressure, respectively. Normal blood pressure at rest is within the range of 100-140mmHg systolic (top reading) and 60-90mmHg diastolic (bottom reading). High blood pressure is said to be present if it is persistently at or above 140/90 mmHg.
Hypertension or high blood pressure is sometimes called "the silent killer" because HBP has no symptoms, so you may not be aware that it's damaging your arteries, heart and other organs. Uncontrolled high blood pressure can injure or kill you. When blood pressure readings rise to 180 or above for the systolic - top - number OR 110 or above for the diastolic - bottom - number, inform your doctor or call for emergency medical treatment immediately. The possible health consequences that can happen over time when high blood pressure is left untreated include:

• Damage to the heart and coronary arteries, including heart attack, heart disease, congestive heart failure, aortic dissection and atherosclerosis (fatty buildups in the arteries that cause them to harden)
• Stroke
• Kidney damage
• Vision loss
• Erectile dysfunction
• Memory loss
• Fluid in the lungs
• Angina
• Peripheral artery disease

Generic Bystolic (Nebistar Tablets) – Product Information

Generic Bystolic (Nebistar Tablets) is a beta-adrenergic blocking agent used for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
The active ingredient present in Generic Bystolic is Nebivolol Hydrochloride. Nebivolol HCl lowers blood pressure (BP) by reducing peripheral vascular resistance, and significantly increases stroke volume with preservation of cardiac output.
Nebivolol Hydrochloride is available as Bystolic, Nebistar, nebilong,  Hypoloc, Lobivon, Nebilet, Nebilox, Nobiten, and Temerit.

Generic Bystolic (Nebistar Tablets) - Contraindications

Generic Bystolic (Nebivolol Hydrochloride Tablets) is contraindicated in patients with

• Hypersensitive to Nebivolol Hydrochloride or any component of the product
• Severe bradycardia
• Heart block greater than first degree
• Cardiogenic shock
• Decompensated cardiac failure
• Sick sinus syndrome (unless a permanent pacemaker is in place)
• Severe hepatic impairment (Child-Pugh > B)

Generic Bystolic (Nebistar Tablets) - Dosage

The adult dosage for Generic Bystolic (Nebistar Tablets) is given below:
Hypertension
The dose of Generic Bystolic has to be individualized as per the needs of the patient. For most patients, the recommended starting dose is 5 mg once daily, with or without food, as monotherapy or in combination with other medicines. For patients requiring further reduction in blood pressure, the dose can be increased at 2-week intervals up to 40 mg.
Renal Impairment
In patients with severe renal impairment (ClCr less than 30 mL/min) the recommended initial dose is 2.5 mg once daily; titrate up slowly if needed.
Hepatic Impairment
In patients with moderate hepatic impairment, the recommended initial dose is 2.5 mg once daily; titrate up slowly if needed. Generic Bystolic has not been studied in patients with severe hepatic impairment and therefore it is not recommended in that population.

Side Effects of Generic Bystolic (Nebistar Tablets)

The most common side effects reported in patients treated with Generic Bystolic (Nebistar Tablets) Bradycardia, Diarrhea, Nausea,Fatigue,Chest pain,Peripheral edema,Headache, Dizziness, Insomnia, Dyspnea, and Rash
The uncommon side effects include asthenia, abdominal pain, hypercholesterolemia and paraesthesia.

Generic Bystolic - More Details

For more details on Generic Bystolic (Nebivolol HCl) please read the Prescription Information or watch the presentation below:

Treatment of Schizophrenia & Bipolar I Disorder with Generic Zyprexa

Generic Zyprexa Tablets (Oleanz Tablets) – Product Information

Generic Zyprexa (Oleanz Tablets, manufactured by SUN Pharma) is used for the treatment of schizophrenia (a mental disease that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) as well as acute treatment of manic or mixed episodes associated with bipolar I disorder and maintenance treatment of bipolar I disorder in adults and adolescents between the ages of 13 to 17 years.
It is also used as an adjunct to valproate or lithium in the treatment of manic or mixed episodes associated with bipolar I disorder in adults. Generic Zyprexa (Oleanz Tablets) is used in Combination with Fluoxetine for the treatment of depressive episodes associated with bipolar I disorder.
The active ingredient present in Generic Zyprexa is Olanzapine. Olanzapine belongs to a class of medications called atypical antipsychotics. It acts by altering the activity of certain natural substances present in the brain.

Generic Zyprexa Tablets (Oleanz Tablets) - Contraindications

Generic Zyprexa is contraindicated in patients with a hypersensitivity to Olanzapine or any other ingredient present in the product.

Generic Zyprexa Tablets (Oleanz Tablets) - Dosage

Oleanz comes as an oral tablet in of 2.5 mg, 5 mg, 7.5 mg, 10 mg and 20 mg dosage forms. Generic Zyprexa (Oleanz Tablets) should be administered on a once-a-day schedule without regard to meals. The recommended adult Oral dosage of Generic Zyprexa for adults is given below:

Dosage for Treatment of Schizophrenia in adults:
Start at 5-10 mg once daily;
Target: 10 mg/day within several days
Dosage for Treatment of Schizophrenia in adolescents:
Oral: Start at 2.5-5 mg once daily;
Target: 10 mg/day

Dosage for Bipolar I Disorder (manic or mixed episodes) in adults:
Start at 10 or 15 mg once daily
Dosage Bipolar I Disorder (manic or mixed episodes) in adolescents:
Start at 2.5-5 mg once daily;
Target: 10 mg/day
Dosage for Treatment of Bipolar I Disorder (manic or mixed episodes) with lithium or valproate in adults
Start at 10 mg once daily.

Dosages have to be individualized. Please Consult your doctor for exact dosing instructions.

Side Effects of Generic Zyprexa Tablets

The most common possible side effects reported in patients treated with Generic Zyprexa Tablets (Oleanz Tablets) (5% and more and at least twice that for placebo) associated with treatment of various indications:
Oral Olanzapine Monotherapy:
Schizophrenia (Adults): postural hypotension, constipation, weight gain, dizziness, personality disorder, akathisia
Schizophrenia (Adolescents): sedation, weight increased, headache, increased appetite, dizziness, abdominal pain, pain in extremity, fatigue, dry mouth
Manic or Mixed Episodes, Bipolar I Disorder (Adults):
asthenia, dry mouth, constipation, increased appetite, somnolence, dizziness, tremor
Manic or Mixed Episodes, Bipolar I Disorder (Adolescents):
sedation, weight increased, increased appetite, headache, fatigue, dizziness, dry mouth, abdominal pain, pain in extremity
Combination of Generic Zyprexa and Lithium or Valproate:
Manic or Mixed Episodes, Bipolar I Disorder (Adults) - dry mouth, weight gain, increased appetite, dizziness, back pain, constipation, speech disorder, increased salivation, amnesia, paresthesia

Generic Zyprexa Tablets (Oleanz Tablets) - More Details

For more details on Generic please read the Prescription Information or watch the presentation below:

Treatment of Asthma and COPD Using Generic Advair Inhaler

Generic Advair Inhaler (Seroflo Inhaler) – Product Information

Generic Advair Inhaler (Seroflo Inhaler, manufactured by Cipla Ltd.) is a combination products which contains a corticosteroid and a Long-acting beta 2-adrenergic agonists (LABA) indicated for treatment of asthma in patients aged 12 years and older. It is also used in the treatment of Chronic obstructive Pulmonary Disease (COPD).
The active ingredients present in Generic Advair Inhaler are Fluticasone Propionate and Salmeterol Xinafoate.
Fluticasone Propionate and Salmeterol Xinafoate inhaler is marketed under trade names such as Advair, Seretide, Seroflo, Viani, Adoair, Quikhale SF and Foxair.

Dosage And Administration

Generic Advair Inhaler (Seroflo Inhaler) comes as an inhaler in 50, 125 and 250 mcg dosage forms.
Seroflo inhalers contain Salmeterol Xinafoate 25 mcg (fixed) and the quantity of Fluticasone Propionate is 50 mcg, 125 mcg or 250 mcg. Seroflo inhaler contains 120 metered doses. Seroflo multihalers contain Salmeterol Xinafoate 50 mcg (fixed) and the quantity of Fluticasone Propionate is 250 mcg or 500 mcg. Seroflo multihaler contains 30 metered doses. The recommended dosage of Generic Advair Inhaler for adults is given below:
Dosage for Treatment of Asthma: Adults and Adolescents (12 years and older):
Seroflo 50 Inhaler: Two inhalations twice daily
Seroflo 125 Inhaler: Two inhalations twice daily
Dosage for Treatment of Asthma: Children (4 years and older)
Seroflo 50 Inhaler: Two inhalations twice daily
Not recommended for children below 4 years of age.
Dosage for Treatment of COPD: Adults:
Seroflo 125 inhaler: Two inhalations twice daily
Seroflo 250 Inhaler: Two inhalations twice daily

Generic Advair Inhaler (Seroflo Inhaler) - Contraindications

Generic Advair Inhaler (Seroflo Inhaler) is contraindicated in patients with a hypersensitivity to Salmeterol Xinafoate or Fluticasone Propionate or any other ingredient present in Seroflo Inhaler. It is also contraindicated in persons with a severe hypersensitivity to milk proteins. Primary treatment of status asthmaticus or acute episodes of asthma or COPD requiring intensive measures using Seroflo Inhaler is also contraindicated.

Generic Advair Inhaler - Warnings and Precautions

Before using Generic Advair Inhaler (Seroflo Inhaler) please inform your doctor of your medical history specially with regard to the following:
current/past infections (such as tuberculosis, herpes), high blood pressure, bone loss (osteoporosis), heart disease (such as chest pain, heart attack, irregular heartbeat), overactive thyroid (hyperthyroidism), diabetes, eye problems (such as cataracts, glaucoma), seizures, liver disease.
The other warnings and precautions are:

• Salmeterol may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
• LABA increase the risk of asthma-related death and asthma-related hospitalizations. Seroflo should not be used in combination with an additional medicine containing LABA because of risk of overdose.
• Seroflo Inhaler should not be used to initiate treatment in acutely deteriorating asthma or COPD or to treat acute symptoms.
• Patients should be monitored periodically as Candida albicans infection of the mouth and pharynx may occur. Patient have to be advised to rinse his/her mouth with water without swallowing after inhalation to help reduce the risk.
• Patients should be monitored for signs and symptoms of pneumonia as there is increased risk of pneumonia in patients with COPD.
• Potential worsening of infections (e.g., existing tuberculosis; fungal, bacterial, viral, or parasitic infection; ocular herpes simplex). Use with caution in patients with these infections. More serious or even fatal course of chickenpox or measles can occur in susceptible patients.
• If paradoxical bronchospasm occurs, discontinue Seroflo Inhaler (Generic Advair Inhaler ) and institute alternative therapy.
• Risk of impaired adrenal function when transferring from systemic corticosteroids.
• Hypercorticism and adrenal suppression may occur with very high dosages or at the regular dosage in susceptible individuals. If such changes occur, discontinue Seroflo slowly.
• Seroflo is to be used with caution in patients with cardiovascular or central nervous system disorders because of beta-adrenergic stimulation.

Side Effects of Generic Advair Inhaler (Seroflo Inhaler)

Generic Advair Inhaler (Fluticasone Propionate and Salmeterol Xinafoate) may cause side effects. The common posssible side effects reported in patients treated with Generic Advair Inhaler (Seroflo Inhaler) include runny nose, sneezing, sore throat, throat irritation, sinus pain, headache, nausea, vomiting, diarrhea, stomach pain, muscle and bone pain, dizziness, weakness, tiredness, sweating, tooth pain, red or dry eyes, shaking of a part of your body that you cannot control and sleep problems.
Some side effects can be serious. If you experience any of the following side effects, call your doctor immediately: coughing, wheezing, or chest tightness that begins soon after you inhale fluticasone and salmeterol, hives, rash, swelling of the face, throat, tongue, lips, hands, feet, ankles, or lower legs, choking or difficulty swallowing, hoarseness, noisy, high-pitched breathing pounding fast, or irregular heartbeat, fainting, chest pain, cough, burning or tingling in the hands or feet, blurred vision, white patches in the mouth, fever, chills, and other signs of infection.

More Details

For more details on Generic Advair Inhaler (Seroflo Inhaler) please read the Prescription Information the presentation below.

Treatment and Prevention of Breast Cancer using Nolvadex Tablets

What is Breast Cancer?

Breast Cancer is a type of cancer originating from breast tissue, most commonly from the inner lining of milk ducts or the lobules that supply the ducts with milk. Cancers originating from ducts are known as ductal carcinomas, while those originating from lobules are known as lobular carcinomas.
Ductal carcinoma in situ (DCIS), or intraductal carcinoma, is breast cancer in the lining of the milk ducts that has not yet spread to nearby tissues. It may progress to invasive cancer if untreated. Lobular carcinoma in situ (LCIS) is a marker for an increased risk of invasive cancer in the same or both breasts.
The size, stage, rate of growth, and other characteristics of a breast cancer determine the type of treatment. Treatment may include surgery, drugs (hormonal therapy and chemotherapy), radiation and/or immunotherapy.
Some breast cancers are sensitive to hormones such as estrogen and/or progesterone, which makes it possible to treat them by blocking the effects of these hormones.

Nolvadex Tablets (Tamoxifen Citrate) – Product Information

Nolvadex Tablets contains the active ingredient Tamoxifen Citrate which works by blocking the actions of oestrogen, a female sex hormone. Nolvadex Tablets are effective in the treatment of metastatic breast cancer in women and men.
Adjuvant Treatment of Breast Cancer. Nolvadex is indicated for the treatment of node-positive breast cancer in postmenopausal women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation.
In women with Ductal Carcinoma in Situ (DCIS), following breast surgery and radiation, Nolvadex is indicated to reduce the risk of invasive breast cancer. Nolvadex is indicated to reduce the incidence of breast cancer in women at high risk for breast cancer.
Tamoxifen is used to treat infertility in women with anovulatory disorders. Tamoxifen is used to prevent estrogen related gynecomastia, resulting from elevated estrogenic levels. It is taken as a preventative measure in small doses, or used at the onset of any symptoms e.g. nipple soreness/sensitivity.

Nolvadex Tablets (Tamoxifen Citrate) - Contraindications

Nolvadex Tablets is contraindicated in patients that have hypersensitivity to Tamoxifen Citrate or any inactive component of this medicine. It is also contraindicated in women who are pregnant or intend to become pregnant within two months after treatment. Women who are breastfeeding or intend to breastfeed, cannot be administered Tamoxifen Citrate as it is unknown if tamoxifen passes into breast milk.

Nolvadex Tablets (Tamoxifen Citrate) - Dosage

Nolvadex Tablets can be taken with or without food at approximately the same time each day. Swallow the tablets with a glass of water. The dosage varies as per the indication being treated. The recommended dosage of Nolvadex tablets for various indications is given below:
Breast Cancer:
For patients with breast cancer, the recommended daily dose of Nolvadex is 20 mg to 40 mg. Dosages greater than 20 mg per day should be given in divided doses (morning and evening).
Ductal Carcinoma in Situ (DCIS):
The recommended dose is 20 mg of Nolvadex daily for 5 years.
Reduction in Breast Cancer Incidence in High Risk Women:
The recommended dose is 20 mg of Nolvadex daily for 5 years.
Infertility (Anovulatory Disorders):
The recommended dosage of Nolvadex Tablets (Tamoxifen Citrate) is 10 mg to 40 mg per day which is is administered in days 3 to 7 of a woman's cycle.

Side Effects of Nolvadex Tablets (Tamoxifen Citrate)

Inform your doctor if you notice any of the following and they worry you: hot flushes, nausea, vomiting, any changes in your period, unusual/changes in vaginal discharge, itching around the genital area, headache, dizziness or light-headedness, diarrhoea or constipation, skin rash, fluid retention, leg cramps and unusual hair loss or thinning. These are the milder side effects of Nolvadex Tablets.
Inform your doctor immediately in case you notice any of the following:

• Abnormal vaginal bleeding
• Unusual pain or pressure around your pelvis, in your bones or anywhere in your body
• Excessive thirst
• Swelling of the hands, ankles and feet
• Lower stomach pain or discomfort.
• Pain and reddening around the tumour
• Unusual tiredness, shortness of breath and dizziness when exercising, and looking pale
• Problems with vision
• Unexplained bruising
• Frequent infection, fever, severe chills, sore throat or mouth ulcers.
• Yellowing of the skin and eyes, and dark coloured urine.

In case of unusual vaginal bleeding or other gynaecological symptoms such as pelvic pain or pressure when you are taking Nolvadex or anytime afterwards, inform your doctor. This is necessary as changes to the lining of the womb may occur, some of which may be serious. Most of the above side effects are rare however you may need urgent medical attention.
Stop taking Nolvadex Tablets and inform your doctor immediately or go to your nearest accident and emergency if you experience any of the following symptoms:

• An unusual cough
• Severe pain in the chest which may reach the left arm
• Breathlessness
• Any unusual, severe or prolonged headache or migraine attack
• Partial or complete loss of vision, or double vision
• Slurring or speech disability
• Sudden changes to your hearing, sense of smell, or taste
• Dizziness or fainting
• Weakness or numbness in any part of your body
• Severe pain in your stomach
• Severe pain or swelling in either of your legs

Increase risk of blood clots and ovarian cysts (in pre-menopausal women) have been seen with Nolvadex Tablets. A blood clot is a very serious side effect. You may need urgent medical attention or hospitalisation. Do not be alarmed by this list of possible side effects. You may not experience any of them.

Nolvadex Tablets (Tamoxifen Citrate) - More Details

For more details please read the prescription information or watch the presentation below:

Prevention of Endometrial Hyperplasia using Generic Prometrium capsules

Generic Prometrium capsules (Micronized Progesterone) – Product Information

Generic Prometrium capsules (Micronized Progesterone) are indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea as well as for maintaining pregnancy.
The active ingredient present in Generic Prometrium Capsules is Micronized Progesterone.
Micronized Progesterone is marketed under trade names such as Prometrium capsules, Utrogestan capsules and Endogest Soft Gelatin capsules. Endogest is available in strengths of 100 mg and 200 mg.

Dosage And Administration

Generic Prometrium (Endogest Soft Gelatin capsules) comes as an oral capsule in 100 mg and 200 mg dosage forms . The recommended adult Oral dosage of Micronized Progesterone Soft Gelatin capsules (Generic Prometrium) for adults is given below:
Prevention of Endometrial Hyperplasia:
Micronized Progesterone capsules should be given as a single daily dose in the evening, 200 mg orally for 12 days sequentially per 28 day cycle, to postmenopausal women with a uterus who are receiving daily conjugated estrogens tablets.
Secondary Amenorrhea:
Micronized Progesterone Capsules may be given as a single daily dose of 400 mg in the evening for 10 days.

Generic Prometrium (Endogest Soft Gelatin capsules) - Contraindications

Generic Prometrium (Endogest Soft Gelatin capsules) is contraindicated in patients that have hypersensitivity to Micronized Progesterone, soya, peanut or to any ingredient in the formulation of the capsule. It is also containdicated in patients with the following conditions:

• active hepatic dysfunction or disease, especially of the obstructive type;
• personal history of known or suspected estrogen dependent or progestin dependent malignant neoplasia (e.g. breast cancer or endometrial cancer)
• endometrial hyperplasia;
• undiagnosed abnormal genital bleeding;
• known or suspected pregnancy;
• active or past history of arterial thromboembolic disease (e.g. stroke, myocardial infarction, coronary heart disease)
• classical migraine;
• active or past history of confirmed venous thromboembolism (such as deep venous thrombosis or pulmonary embolism) or active thrombophlebitis;
• partial or complete loss of vision due to ophthalmic vascular disease

Side Effects of Generic Prometrium (Endogest Soft Gelatin capsules)

The common possible side effects reported in patients treated with Generic Prometrium (Endogest Soft Gelatin capsules) include Headache, Breast Tenderness, Joint Pain, Depression, Dizziness, Abdominal Bloating, Hot Flashes, Urinary Problems, Abdominal Pain, Vaginal Discharge, Nausea / Vomiting, Worry, Chest Pain, Diarrhea, Night Sweats, Breast Pain, Swelling of Hands and Feet, Vaginal Dryness, Constipation, Breast Carcinoma, Breast Excisional Biopsy and Cholecystectomy.

More Details on Generic Prometrium Capsules

For more details on Generic Prometrium (Endogest Soft Gelatin capsules) please read the prescription information or watch the presentation below.

Treatment of Hypertension & Oedematous Disorders with Aldactone Tablets

Aldactone Tablets (Spironolactone) – Product Information

Aldactone Tablets manufactured by RPG Life Science Ltd. are used to treat essential hypertension (high blood pressure with an unknown cause), oedematous disorders(swelling with fluid), including congestive cardiac failure, diagnosis and treatment of primary aldosteronism, reducing or preventing potassium loss due to thiazide diuretics, add-on therapy in malignant hypertension, prevention of low amounts of potassium in the blood in patients taking digitalis, treatment of hirsutism, treatment of patients with hypokalemia when other measures are considered inappropriate or inadequate and other conditions. Aldactone is available as tablets of 25 mg and 100 mg . Aldactone oral tablets contain 25 mg or 100 mg of the active ingredient spironolactone respectively.
Aldactone acts by working against the effects of a hormone called aldosterone. Too much aldosterone causes increased amounts of sodium (a mineral) and water to be retained by the kidneys, while too much potassium is removed from the body.
Aldactone also has a moderate ability to act against male sex hormones (anti-androgenic effect). Because of this, Aldactone is effective in the treatment of female hirsutism (excess body hair). It reduces hair growth, thickness and hair colour.

Aldactone Tablets - Contraindications

Aldactone is contraindicated in patients that have hypersensitivity to Spironolactone or any inactive component of this medicine. Aldactone Tablets are also contraindicated for patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, Addison's disease or hyperkalemia, pregnancy or with concomitant use of eplerenone.

Aldactone Tablets - Dosage

The recommended dosage of Aldactone Tablets for various indications is given below:
Establishing the diagnosis of Primary Hyperaldosteronism:
Long test: ALDACTONE is administered at a daily dosage of 400 mg for three to four weeks.
Short test: ALDACTONE is administered at a daily dosage of 400 mg for four days.
Edema in adults (congestive heart failure, hepatic cirrhosis, or nephrotic syndrome):
An initial daily dosage of 100 mg of Aldactone administered in either single or divided doses is recommended, but may range from 25 to 200 mg daily. When given as the sole agent for diuresis, Aldactone should be continued for at least five days at the initial dosage level, after which it may be adjusted to the optimal therapeutic or maintenance level.
Essential hypertension:
For adults, an initial daily dosage of 50 to 100 mg of Aldactone administered in either single or divided doses is recommended.
Hypokalemia:
Aldactone in a dosage ranging from 25 mg to 100 mg daily is useful in treating a diuretic-induced hypokalemia, when oral potassium supplements or other potassium-sparing regimens are considered inappropriate.
Severe Heart Failure (NYHA class III – IV):
Treatment should be started with Aldactone 25 mg once daily if the patient’s serum potassium is equal to 5.0 mEq/L and the patient’s serum creatinine is equal to 2.5 mg/dL. Patients who tolerate 25 mg once daily may have their dosage increased to 50 mg once daily as clinically indicated. Patients who do not tolerate 25 mg once daily may have their dosage reduced to 25 mg every other day.

Side Effects of Aldactone Tablets

The side effects of Aldactone Tablets include:
Digestive: Gastric bleeding, ulceration, gastritis, diarrhea and cramping, nausea, vomiting.
Endocrine: Gynecomastia (see Precautions), inability to achieve or maintain erection, irregular menses or amenorrhea, postmenopausal bleeding. Carcinoma of the breast has been reported in patients taking Aldactone but a cause and effect relationship has not been established.
Hematologic: Agranulocytosis.
Hypersensitivity: Fever, urticaria, maculopapular or erythematous cutaneous eruptions, anaphylactic reactions, vasculitis.
Metabolism: Hyperkalemia.
Nervous system /psychiatric: Mental confusion, ataxia, headache, drowsiness, lethargy.
Liver / biliary: A very few cases of mixed cholestatic/hepatocellular toxicity, with one reported fatality, have been reported with Aldactone administration.
Renal: Renal dysfunction (including renal failure).

Aldactone Tablets - More Details

For more details please read the prescription information or watch the presentation below:

Treatment of Depression Using Generic Effexor XR Capsules

What is Depression?

Everyone occasionally feels sad, blue,unhappy, miserable, or down in the dumps. These feelings are usually short-lived and pass within a couple of days. When you have Clinical Depression , it interferes with daily life for weeks or longer and causes pain for both you and those who care about you. Depression is a common but serious illness which can get better with treatment. Medications, psychotherapies, and other methods can effectively treat people with depression.
Depressive illnesses are disorders of the brain and are most likely to be caused by a combination of genetic, biological, environmental, and psychological factors.
A person is diagnosed with depression can be treated in several ways. The most common treatments are medication and psychotherapy. Antidepressants primarily work on brain chemicals called neurotransmitters, especially serotonin and norepinephrine. Other antidepressants work on the neurotransmitter dopamine.
The newest and most popular antidepressants are called selective serotonin reuptake inhibitors (SSRIs) which include Fluoxetine (Prozac), sertraline (Zoloft), escitalopram (Lexapro), paroxetine (Paxil), and citalopram (Celexa) are some of the most commonly prescribed SSRIs for depression. Serotonin and norepinephrine reuptake inhibitors (SNRIs) are similar to SSRIs and include venlafaxine (Effexor) and duloxetine (Cymbalta). Most are available in generic versions such as Venlor XR Capsules manufactured by Cipla Ltd., India is a generic version of Effexor XR (Venlafaxine)

Generic Effexor XR (Venlor XR Capsules) – Product Information

Generic Effexor XR is used in the treatment and prevention of relapse of depression. Effexor XR (venlafaxine hydrochloride) extended-release capsules is indicated for the treatment of major depressive disorder, Generalized Anxiety Disorder (GAD), Social Anxiety Disorder, also known as Social Phobia as well as for the treatment of panic disorder. It is also used for the prevention of relapses of the initial episode of depression or for the prevention of the recurrence of new depressive episodes. The active ingredient present in Generic Effexor XR is Venlafaxine Hydrochloride. Venlor XR is manufactured by Cipla Ltd. in strengths of 37.5 mg, 75 mg and 150 mg. The capsules contain venlafaxine hydrochloride equivalent to 37.5 mg, 75 mg, or 150 mg venlafaxine respectively.

Generic Effexor XR - Contraindications

Generic Effexor XR is contraindicated in patients that have hypersensitivity to Venlafaxine Hydrochloride or any inactive component of this medicine. Concomitant use with MAOIs is also contraindicated. Generic Effexor XR is also contraindicated in patients aged below 18 years, patients with very high risk of a serious cardiac ventricular arrhythmia, uncontrolled hypertension.

Generic Effexor XR (Venlor XR Capsules) - Dosage

Generic Effexor XR should be administered in a single dose with food either in the morning or in the evening at approximately the same time each day. Each capsule should be swallowed whole with fluid and not divided, crushed, chewed, or placed in water. The dosage varies as per the indication being treated.The recommended dosage of Venlor XR Capsules for various indications is given below:
Major Depressive Disorder:
For most patients, the recommended starting dose for Effexor XR is 75 mg/day, administered in a single dose.
Generalized Anxiety Disorder:
For most patients, the recommended starting dose for Effexor XR is 75 mg/day, administered in a single dose.
Social Anxiety Disorder (Social Phobia):
The recommended dose of Generic Effexor XR (Venlafaxine Hydrochloride) is 75 mg/day, administered in a single dose.
Panic Disorder:
The recommended initial dose of Generic Effexor XR is a single dose of 37.5 mg/day for 7 days.

Side Effects of Generic Effexor XR

The adverse events most commonly associated with Venlor XR (Generic Effexor XR Capsules)administration are nervous system complaints, such as headache, dizziness, insomnia, somnolence, nervousness and dry mouth; gastrointestinal complaints, including anorexia, nausea and constipation; and abnormal ejaculation/orgasm, sweating and asthenia. Many of the frequently observed adverse events are dose related. With continued theatment, these adverse effects generally decrease in frequency and intensity, and usually do not require discontinuation.

Generic Effexor XR - More Details

For more details please read the prescription information or watch the presentation below: