What is hypertension?
Hypertension or high blood pressure, sometimes called arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is elevated. This requires the heart to work harder than normal to circulate blood through the blood vessels. Blood pressure is summarised by two measurements, systolic and diastolic, which depend on whether the heart muscle is contracting (systole) or relaxed between beats (diastole) and equate to a maximum and minimum pressure, respectively. Normal blood pressure at rest is within the range of 100-140mmHg systolic (top reading) and 60-90mmHg diastolic (bottom reading). High blood pressure is said to be present if it is persistently at or above 140/90 mmHg.
Hypertension or high blood pressure is sometimes called "the silent killer" because HBP has no symptoms, so you may not be aware that it's damaging your arteries, heart and other organs. Uncontrolled high blood pressure can injure or kill you. When blood pressure readings rise to 180 or above for the systolic - top - number OR 110 or above for the diastolic - bottom - number, inform your doctor or call for emergency medical treatment immediately. The possible health consequences that can happen over time when high blood pressure is left untreated include:
- Damage to the heart and coronary arteries, including heart attack, heart disease, congestive heart failure, aortic dissection and atherosclerosis (fatty buildups in the arteries that cause them to harden)
- Stroke
- Kidney damage
- Vision loss
- Erectile dysfunction
- Memory loss
- Fluid in the lungs
- Angina
- Peripheral artery disease
Generic Bystolic (Nebistar Tablets) – Product Information
Generic Bystolic (Nebistar Tablets) is a beta-adrenergic blocking agent used for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
The active ingredient present in Generic Bystolic is Nebivolol Hydrochloride. Nebivolol HCl lowers blood pressure (BP) by reducing peripheral vascular resistance, and significantly increases stroke volume with preservation of cardiac output.
Nebivolol Hydrochloride is available as Bystolic, Nebistar, nebilong, Hypoloc, Lobivon, Nebilet, Nebilox, Nobiten, and Temerit.
Generic Bystolic (Nebistar Tablets) - Contraindications
Generic Bystolic (Nebivolol Hydrochloride Tablets) is contraindicated in patients with
- Hypersensitive to Nebivolol Hydrochloride or any component of the product
- Severe bradycardia
- Heart block greater than first degree
- Cardiogenic shock
- Decompensated cardiac failure
- Sick sinus syndrome (unless a permanent pacemaker is in place)
- Severe hepatic impairment (Child-Pugh > B)
Generic Bystolic (Nebistar Tablets) - Dosage
The adult dosage for Generic Bystolic (Nebistar Tablets) is given below:
Hypertension
The dose of Generic Bystolic has to be individualized as per the needs of the patient. For most patients, the recommended starting dose is 5 mg once daily, with or without food, as monotherapy or in combination with other medicines. For patients requiring further reduction in blood pressure, the dose can be increased at 2-week intervals up to 40 mg.
Renal Impairment
In patients with severe renal impairment (ClCr less than 30 mL/min) the recommended initial dose is 2.5 mg once daily; titrate up slowly if needed.
Hepatic Impairment
In patients with moderate hepatic impairment, the recommended initial dose is 2.5 mg once daily; titrate up slowly if needed. Generic Bystolic has not been studied in patients with severe hepatic impairment and therefore it is not recommended in that population.
Side Effects of Generic Bystolic (Nebistar Tablets)
The most common side effects reported in patients treated with Generic Bystolic (Nebistar Tablets) Bradycardia, Diarrhea, Nausea,Fatigue,Chest pain,Peripheral edema,Headache, Dizziness, Insomnia, Dyspnea, and Rash
The uncommon side effects include asthenia, abdominal pain, hypercholesterolemia and paraesthesia.
Generic Bystolic - More Details
For more details on Generic Bystolic (Nebivolol HCl) please read the Prescription Information or watch the presentation below:
