What is Primary Dysmenorrhea?
Dysmenorrhea can include different kinds of pain, including sharp, throbbing, dull, nauseating, burning, or shooting pain. Dysmenorrhea may precede menstruation by several days or may accompany it, and it usually subsides as menstruation tapers off. Dysmenorrhea may coexist with excessively heavy blood loss, known as menorrhagia.
Primary dysmenorrhea is menstrual pain that's not a symptom of an underlying gynecologic disorder but is related to the normal process of menstruation. It often begins with the onset of ovulatory cycles six months to one year after the first menstrual cycle. The pain begins with the onset of the period and may last for 24-72 hours.
Primary dysmenorrhea is more likely to affect girls during adolescence. Fortunately for many women, the problem eases as they mature, particularly after a pregnancy. Although it may be painful and sometimes debilitating for brief periods of time, it is not harmful.
What is Pyrexia?
Fever, also known as Pyrexia is one of the most common medical signs and is characterized by an elevation of body temperature above the normal range of 36.5-37.5°C (97.7-99.5 °F) due to an increase in the temperature regulatory set-point. As a person's temperature increases, there is, in general, a feeling of cold despite an increase in body temperature.
With the exception of very high temperatures, treatment to reduce fever is often not necessary; however, antipyretic medications can be effective at lowering the temperature, which may improve the affected person's comfort.
Brufen Tablets – Product Information
Brufen Tablets (Ibuprofen) is used for relief of the signs and symptoms of Rheumatoid arthritis, Osteoarthritis, Juvenile rheumatoid arthritis, Primary dysmenorrhoea, and Pyrexia. Brufen is also used for the relief of acute and/or chronic pain states in which there is an inflammatory component.
The active ingredient present in Brufen Tablets is Ibuprofen.
Ibuprofen is marketed under trade names such as Motrin, Brufen, Ibugesic, Advil, Nuprin, Calprofen, Ribafen, Nurofen.
Brufen Tablets - Contraindications
Brufen Tablets is contraindicated for patients with hypersensitivity to Ibuprofen or any of the inactive ingredients present in Brufen tablets.
Hypersensitivity (e.g. asthma, rhinitis or urticaria) to aspirin or other nonsteroidal anti-inflammatory drugs. Ibuprofen should not be used in active gastrointestinal bleeding
or perforation related to previous NSAID therapy. Ibuprofen should not be used in patients with active, or a history of, ulcerative colitis, Crohn's disease, recurrent peptic
ulceration or gastrointestinal haemorrhage.
Brufen Tablets - Dosage
Brufen Tablets comes as an oral tablet in 200 mg, 400 mg and 600 mg dosage forms. The recommended adult Oral dosage of Brufen Tablets for adults is given below:
Recommended Adult Dosage:
The recommended initial dosage of Brufen tablets is 1200 mg to 1800 mg daily in divided doses. Some patients can be maintained on 600 to 1200 mg daily. In severe or acute conditions it can be advantageous to increase the dosage until the acute phase is brought under control, providing that the total daily dosage does not exceed 2400mg in divided doses.
Primary Dysmenorrhoea:
For the treatment of dysmenorrhea, beginning with the earliest onset of such pain or menstrual bleeding, Ibuprofen tablets should be given in a dose of 400 mg every 4 to 6 hours as necessary with amaximum total daily dose of 1,600 mg.
Mild to Moderate Pain:
The recommended adult dosage is 400 mg every 4 to 6 hours as necessary for relief of pain.
Maintenance Dose:
In all indications the doses should be adjusted for each patient and the smallest dose that results in acceptable control of the symptoms employed. In general, patients with rheumatoid arthritis and osteo arthritis tend to require higher doses than patients with other conditions.
Side Effects of Brufen Tablets
The common possible side effects reported in patients treated with Brufen Tablets include Nausea, epigastric pain, heartburn, diarrhea, abdominal distress, nausea and vomiting, indigestion, constipation, abdominal cramps or pain, fullness of GI tract (bloating and flatulence),Dizziness, headache, nervousness, Rash (including maculopapular type), pruritus, Tinnitus, decreased appetite, Edema, and fluid retention.
Rare side effects include Gastic or duodenal ulcer with bleeding and/or perforation, gastrointestinal hemorrhage, melena, gastritis, hepatitis, jaundice, abnormal liver function tests; pancreatitis, Depression, insomina, confusion, emotional lability, somnolence, aseptic meningitis with fever and coma, vesiculobullous eruptions, urticaria, erythema multiforme, Stevens-Johnson syndrome, alopecia,hearing loss, amblyopia (blurred and/or diminished vision, scotomata and/or changes in color vision), neutropenia, agranulocytosis, aplastic anemia, hemolytic anemia (sometimes Coombs Positive), thrombocytopenia with or without purpura, eosinophilia, decreases in hemoglobin and hematocrit, congestive heart failure in patients with marginal cardiac function, elevated blood pressure, palpitations, Syndrome of abdominal pain, fever, chills, nausea and vomiting; anaphylaxis; bronchospasm, acute renal failure, decreased creatinine clearance, polyuria, azotemia, cystitis, hematuria, dry eyes and mouth, gingival ulcer and rhinitis.
Brufen Tablets - More Details
For more details on Brufen Tablets please read the Prescription Information or watch the presentation below:
