Treatment of Asthma and COPD using Generic Symbicort Inhaler

Generic Symbicort (Foracort Inhaler) – Product Information

Generic Symbicort (Foracort Inhaler, manufactured by Cipla) is a combination of two medicines Formoterol Fumarate and Budesonide.
Budesonide is a glucocorticoid steroid that reduces inflammation. Formoterol Fumarate is a bronchodilator that relaxes muscles in the airways of the lungs to improve breathing. Generic Symbicort Inhaler is used treat asthma in patients 12 years of age and older. It is also used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema

Generic Symbicort (Foracort Inhaler) - Contraindications

Generic Symbicort (Foracort Inhaler) is contraindicated in patients with a hypersensitivity to Formoterol Fumarate, Budesonide or any inactive ingredient present in Foracort Inhaler. It is also contraindicated for primary treatment of status asthmaticus or acute episodes of asthma or COPD requiring intensive measures.

Generic Symbicort (Foracort Inhaler) - Dosage

Foracort Inhaler comes as an inhaler in 100mcg, 200mcg and 400mcg dosage forms. Each dose of Foracort 100 Inhaler delivers Formoterol Fumarate 6mcg and Budesonide 100 mcg, Foracort 200 Inhaler delivers Formoterol Fumarate 6 mcg and Budesonide 200 mcg, Foracort 400 Inhaler delivers Formoterol Fumarate 6 mcg and Budesonide 400 mcg. The recommended adult Oral dosage of Generic for adults is given below:
For Asthma:
The recommended dosage for patients 18 years and older is 1-2 inhalations of Foracort 100 (Formoterol Fumarate 6mcg + Budesonide 100 mcg) twice daily with a maximum of 4 inhalations twice daily.

Generic Symbicort (Foracort Inhaler) - Warnings and Precautions

The following precautions are to be observed when undergoing treatment using Generic Symbicort inhaler:

• Treatment with Foracort inhaler should not be initiated to treat a severe exacerbation or if patients have significantly worsening or acutely deteriorating asthma.
• The lowest effective dose of Generic Symbicort inhaler should be used.
• Patients should be reminded to take their Foracort maintenance dose as prescribed, even when asymptomatic.
• Once asthma symptoms are controlled, consideration may be given to stepping down treatment with Generic Symbicort inhaler.
• When long-term treatment with Generic Symbicort inhaler is to be discontinued, the dose should be tapered.

Side Effects of Generic Symbicort (Foracort Inhaler)

The possible side effects reported in patients treated with Generic Symbicort inhaler are listed below:
Common:
Palpitations, candida infection in the oropharynx, headache, tremor, mild irritation in the throat, coughing, hoarseness.
Uncommon:
Tachycardia, nausea, bruises, muscle cramps, dizziness, agitation, restlessness, nervousness, sleep disturbances.
Rare:
Cardiac arrhythmias, e.g. atrial fibrillation, supraventricular tachycardia, extrasystoles. Immediate and delayed hypersensitivity reactions, e.g. dermatitis, exanthema, urticaria, pruritus and angioedema. Bronchospasm, hypokalaemia.
Very rare:
Angina pectoris, signs and symptoms of systemic glucocorticosteroid effects, e.g. hypofunction of the adrenal gland, growth retardation, decrease in bone mineral density. Hyperglycaemia, depression, behavioural disturbances, taste disturbances, cataract, glaucoma.

Generic Symbicort (Foracort Inhaler) - More Details

For more details please read the Prescription Information or watch the presentation below:

Generic Symbicort Inhaler for Treatment of Asthma & COPD

Treatment of COPD using Generic Spiriva Inhaler

Generic Spiriva Inhaler (Tiova Inhaler) – Product Information

Tiova Inhaler, manufactured by Cipla Ltd. (Generic Spiriva) is a long-acting, 24 hour, anticholinergic bronchodilator which is used to for the long-term, once-daily, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease(COPD) which includes bronchitis and emphysema.
Generic Spiriva works by relaxing the muscles around the airways so that they open up and enables patients to breathe more easily.
The active ingredient present in Generic Spiriva Inhaler is Tiotropium Bromide.
Tiotropium Bromide Inhaler is marketed under trade names such as Spiriva and Tiova. It is also available as a dry inhalation powder under the same brand names.

Generic Spiriva Inhaler - Contraindications

Generic Spiriva Inhaler (Tiova Inhaler) is contraindicated in patients with a hypersensitivity to to Tiotropium, Ipratropium, or any inactive component of this medication.

Generic Spiriva Inhaler (Tiova Inhaler) - Dosage

Tiova Inhaler (Generic Spiriva ) comes as an inhaler with 120 metered doses in 9 mcg dosage forms.The recommended adult Oral dosage of Generic Spiriva for adults is given below:
Dosage for Treatment of Adults
The maximum dose of Tiotropium Bromide is 18 mcg (2 puffs of Tiova Inhaler) which is administered by the inhalation device.

Generic Spiriva Inhaler (Tiova Inhaler) - Warnings and Precautions

The warnings and precautions to be taken when undergoing treatment with Tiova Inhaler are given below:

• Not for emergency use: Generic Spiriva Inhaler is not for acute use, i.e., not a rescue medication
• Immediate hypersensitivity reactions: Discontinue Generic Spiriva at once and consider alternatives if immediate hypersensitivity reactions, including angioedema, bronchospasm, or anaphylaxis, occur.
• Paradoxical bronchospasm: Discontinue Generic Spiriva and consider other treatments if paradoxical bronchospasm occurs.
• Worsening of narrow-angle glaucoma may occur. Use with caution in patients with narrow-angle glaucoma and instruct patients to consult a physician immediately if this occurs.
• Worsening of urinary retention may occur. Use with caution in patients with prostatic hyperplasia or bladder-neck obstruction and instruct patient to consult a physician immediately if this occurs.

Side Effects of Generic Spiriva Inhaler (Tiova Inhaler)

The common possible side effects reported in patients treated with Tiova Inhaler (Generic Spiriva) include pharyngitis, cough, dry mouth and/or throat irritation and sinusitis . Rarely occuring side effects that occur in less than 0.1% of patients undergoing treatment are urinary retention, constipation, acute angle closure glaucoma, palpitations (notably supraventricular tachycardia and atrial fibrillation) and/or allergy (rash, angioedema, anaphylaxis).

Generic Spiriva Inhaler (Tiova Inhaler) - More Details

For more details please read the Prescription Information or watch the presentation below:

Generic Spiriva Inhaler for Treatment of COPD

Treatment of Asthma and COPD Using Generic Advair Inhaler

Generic Advair Inhaler (Seroflo Inhaler) – Product Information

Generic Advair Inhaler (Seroflo Inhaler, manufactured by Cipla Ltd.) is a combination products which contains a corticosteroid and a Long-acting beta 2-adrenergic agonists (LABA) indicated for treatment of asthma in patients aged 12 years and older. It is also used in the treatment of Chronic obstructive Pulmonary Disease (COPD).
The active ingredients present in Generic Advair Inhaler are Fluticasone Propionate and Salmeterol Xinafoate.
Fluticasone Propionate and Salmeterol Xinafoate inhaler is marketed under trade names such as Advair, Seretide, Seroflo, Viani, Adoair, Quikhale SF and Foxair.

Dosage And Administration

Generic Advair Inhaler (Seroflo Inhaler) comes as an inhaler in 50, 125 and 250 mcg dosage forms.
Seroflo inhalers contain Salmeterol Xinafoate 25 mcg (fixed) and the quantity of Fluticasone Propionate is 50 mcg, 125 mcg or 250 mcg. Seroflo inhaler contains 120 metered doses. Seroflo multihalers contain Salmeterol Xinafoate 50 mcg (fixed) and the quantity of Fluticasone Propionate is 250 mcg or 500 mcg. Seroflo multihaler contains 30 metered doses. The recommended dosage of Generic Advair Inhaler for adults is given below:
Dosage for Treatment of Asthma: Adults and Adolescents (12 years and older):
Seroflo 50 Inhaler: Two inhalations twice daily
Seroflo 125 Inhaler: Two inhalations twice daily
Dosage for Treatment of Asthma: Children (4 years and older)
Seroflo 50 Inhaler: Two inhalations twice daily
Not recommended for children below 4 years of age.
Dosage for Treatment of COPD: Adults:
Seroflo 125 inhaler: Two inhalations twice daily
Seroflo 250 Inhaler: Two inhalations twice daily

Generic Advair Inhaler (Seroflo Inhaler) - Contraindications

Generic Advair Inhaler (Seroflo Inhaler) is contraindicated in patients with a hypersensitivity to Salmeterol Xinafoate or Fluticasone Propionate or any other ingredient present in Seroflo Inhaler. It is also contraindicated in persons with a severe hypersensitivity to milk proteins. Primary treatment of status asthmaticus or acute episodes of asthma or COPD requiring intensive measures using Seroflo Inhaler is also contraindicated.

Generic Advair Inhaler - Warnings and Precautions

Before using Generic Advair Inhaler (Seroflo Inhaler) please inform your doctor of your medical history specially with regard to the following:
current/past infections (such as tuberculosis, herpes), high blood pressure, bone loss (osteoporosis), heart disease (such as chest pain, heart attack, irregular heartbeat), overactive thyroid (hyperthyroidism), diabetes, eye problems (such as cataracts, glaucoma), seizures, liver disease.
The other warnings and precautions are:

• Salmeterol may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
• LABA increase the risk of asthma-related death and asthma-related hospitalizations. Seroflo should not be used in combination with an additional medicine containing LABA because of risk of overdose.
• Seroflo Inhaler should not be used to initiate treatment in acutely deteriorating asthma or COPD or to treat acute symptoms.
• Patients should be monitored periodically as Candida albicans infection of the mouth and pharynx may occur. Patient have to be advised to rinse his/her mouth with water without swallowing after inhalation to help reduce the risk.
• Patients should be monitored for signs and symptoms of pneumonia as there is increased risk of pneumonia in patients with COPD.
• Potential worsening of infections (e.g., existing tuberculosis; fungal, bacterial, viral, or parasitic infection; ocular herpes simplex). Use with caution in patients with these infections. More serious or even fatal course of chickenpox or measles can occur in susceptible patients.
• If paradoxical bronchospasm occurs, discontinue Seroflo Inhaler (Generic Advair Inhaler ) and institute alternative therapy.
• Risk of impaired adrenal function when transferring from systemic corticosteroids.
• Hypercorticism and adrenal suppression may occur with very high dosages or at the regular dosage in susceptible individuals. If such changes occur, discontinue Seroflo slowly.
• Seroflo is to be used with caution in patients with cardiovascular or central nervous system disorders because of beta-adrenergic stimulation.

Side Effects of Generic Advair Inhaler (Seroflo Inhaler)

Generic Advair Inhaler (Fluticasone Propionate and Salmeterol Xinafoate) may cause side effects. The common posssible side effects reported in patients treated with Generic Advair Inhaler (Seroflo Inhaler) include runny nose, sneezing, sore throat, throat irritation, sinus pain, headache, nausea, vomiting, diarrhea, stomach pain, muscle and bone pain, dizziness, weakness, tiredness, sweating, tooth pain, red or dry eyes, shaking of a part of your body that you cannot control and sleep problems.
Some side effects can be serious. If you experience any of the following side effects, call your doctor immediately: coughing, wheezing, or chest tightness that begins soon after you inhale fluticasone and salmeterol, hives, rash, swelling of the face, throat, tongue, lips, hands, feet, ankles, or lower legs, choking or difficulty swallowing, hoarseness, noisy, high-pitched breathing pounding fast, or irregular heartbeat, fainting, chest pain, cough, burning or tingling in the hands or feet, blurred vision, white patches in the mouth, fever, chills, and other signs of infection.

More Details

For more details on Generic Advair Inhaler (Seroflo Inhaler) please read the Prescription Information the presentation below.