Generic Cymbalta Capsules – Product Information
Generic Cymbalta Capsules belongs to a category of medications called Serotonin and Norepinephrine Reuptake Inhibitor (SNRI) which work to increase the amounts of serotonin and norepinephrine, naturally occuring chemicals in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
Generic Cymbalta Capsules are used to treat Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Diabetic Peripheral Neuropathic Pain (DPNP), Fibromyalgia (FM) and Chronic Musculoskeletal Pain.
It is available as Dulot capsules ( Lupin Ltd. ), Duzela capsules (Sun Pharma) and Duvanta tablets (Intas Pharmaceuticals Ltd). The active ingredient pharmaceutical present in Generic Cymbalta is Duloxetine.
Duloxetine is also marketed under brand names such as Ariclaim, Xeristar, Yentreve, Duzela, Dulane, Cymbalta, and Cymgen (in South Africa).
Generic Cymbalta Capsules - Contraindications
Use of Generic Cymbalta is contraindicated to treat patients with the following conditions:
- Generic Cymbalta Capsules are contraindicated in patients with ahypersensitivity to Duloxetine or any inactive ingredient present in generic Cymbalta capsules.
- Generic Cymbalta is contraindicated in patients with hepatic impairment.
- Generic Cymbalta should not be used in combination with potent CYP1A2 inhibitors
- The use of Monoamine Oxidase Inhibitors (MAOIs) to treat psychiatric disorders with Generic Cymbalta or within five days of stopping treatment with Generic Cymbalta is contraindicated because of an increased risk of serotonin syndrome. Additionally the use of Generic Cymbalta within 14 days of stopping an MAOI intended to treat psychiatric disorders is also contraindicated.
- Starting treatment with Generic Cymbalta in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome.
Generic Cymbalta - Dosage
Generic Cymbalta (Duloxetine) comes as oral Capsules in 20 mg, 30 mg, 40 mg and 60 mg dosage forms. Take Generic Cymbalta once daily, with or without food. Generic Cymbalta capsules have to be swallowed whole. You must not crush or chew and the capsule should not be opened. The recommended adult Oral dosage of Generic Cymbalta is given below:
Dosage for Treatment of Major Depressive Disorder (MDD):
Starting Dose: 40mg/day to 60mg/day
Target Dose Acute Treatment: 40 mg/day (20 mg twice daily) to 60 mg/day (once daily or as 30 mg twice daily);
Target Dose Maintenance Treatment: 60 mg/day
Dosage for Treatment of Diabetic Peripheral Neuropathic Pain (DPNP):
Starting Dose: 60mg/day
Target Dose: 60 mg/day (once daily)
Dosage for Treatment of Generalized Anxiety Disorder (GAD):
Starting Dose:60mg/day
Target Dose: 60 mg/day (once daily)
Dosage for Treatment of Fibromyalgia (FM):
Starting Dose:30mg/day
Target Dose: 60 mg/day (once daily)
Dosage for Treatment of Chronic Musculoskeletal Pain:
Starting Dose: 30mg/day
Target Dose: 60 mg/day (once daily)
Side Effects of Generic Cymbalta
The most common side effects reported in patients treated with Generic Cymbalta include nausea, vomiting, constipation, diarrhea, heartburn, stomach pain, decreased appetite, dry mouth, increased urination, difficulty urinating, sweating or night sweats, dizziness, headache, tiredness, weakness, drowsiness, muscle pain or cramps, changes in sexual desire or ability, uncontrollable shaking of a part of the body. Please inform your doctor if any of the above symptoms are severe or do not go away.
In case you experience any of the following serious side effects listed below, call your doctor immediately or get emergency medical treatment:
- unusual bruising or bleeding
- pain in the upper right part of the stomach
- swelling of the abdomen
- itching
- yellowing of the skin or eyes
- dark colored urine
- loss of appetite
- extreme tiredness or weakness
- confusion
- flu-like symptoms
- fever, sweating, confusion, fast or irregular heartbeat, and severe muscle stiffness
- fever
- blisters or peeling skin
- rash
- hives
- difficulty breathing or swallowing
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- hoarseness
Generic Cymbalta - More Details
For more details on Generic please read the Prescription Information or watch the presentation below:
