Monday 24 November 2014

Treatment of Asthma and COPD using Generic Symbicort Inhaler

Generic Symbicort (Foracort Inhaler) – Product Information

Generic Symbicort (Foracort Inhaler, manufactured by Cipla) is a combination of two medicines Formoterol Fumarate and Budesonide.
Budesonide is a glucocorticoid steroid that reduces inflammation. Formoterol Fumarate is a bronchodilator that relaxes muscles in the airways of the lungs to improve breathing. Generic Symbicort Inhaler is used treat asthma in patients 12 years of age and older. It is also used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema

Generic Symbicort (Foracort Inhaler) - Contraindications

Generic Symbicort (Foracort Inhaler) is contraindicated in patients with a hypersensitivity to Formoterol Fumarate, Budesonide or any inactive ingredient present in Foracort Inhaler. It is also contraindicated for primary treatment of status asthmaticus or acute episodes of asthma or COPD requiring intensive measures.

Generic Symbicort (Foracort Inhaler) - Dosage

Foracort Inhaler comes as an inhaler in 100mcg, 200mcg and 400mcg dosage forms. Each dose of Foracort 100 Inhaler delivers Formoterol Fumarate 6mcg and Budesonide 100 mcg, Foracort 200 Inhaler delivers Formoterol Fumarate 6 mcg and Budesonide 200 mcg, Foracort 400 Inhaler delivers Formoterol Fumarate 6 mcg and Budesonide 400 mcg. The recommended adult Oral dosage of Generic for adults is given below:
For Asthma:
The recommended dosage for patients 18 years and older is 1-2 inhalations of Foracort 100 (Formoterol Fumarate 6mcg + Budesonide 100 mcg) twice daily with a maximum of 4 inhalations twice daily.

Generic Symbicort (Foracort Inhaler) - Warnings and Precautions

The following precautions are to be observed when undergoing treatment using Generic Symbicort inhaler:

  • Treatment with Foracort inhaler should not be initiated to treat a severe exacerbation or if patients have significantly worsening or acutely deteriorating asthma.
  • The lowest effective dose of Generic Symbicort inhaler should be used.
  • Patients should be reminded to take their Foracort maintenance dose as prescribed, even when asymptomatic.
  • Once asthma symptoms are controlled, consideration may be given to stepping down treatment with Generic Symbicort inhaler.
  • When long-term treatment with Generic Symbicort inhaler is to be discontinued, the dose should be tapered.

Side Effects of Generic Symbicort (Foracort Inhaler)

The possible side effects reported in patients treated with Generic Symbicort inhaler are listed below:
Common:
Palpitations, candida infection in the oropharynx, headache, tremor, mild irritation in the throat, coughing, hoarseness.
Uncommon:
Tachycardia, nausea, bruises, muscle cramps, dizziness, agitation, restlessness, nervousness, sleep disturbances.
Rare:
Cardiac arrhythmias, e.g. atrial fibrillation, supraventricular tachycardia, extrasystoles. Immediate and delayed hypersensitivity reactions, e.g. dermatitis, exanthema, urticaria, pruritus and angioedema. Bronchospasm, hypokalaemia.
Very rare:
Angina pectoris, signs and symptoms of systemic glucocorticosteroid effects, e.g. hypofunction of the adrenal gland, growth retardation, decrease in bone mineral density. Hyperglycaemia, depression, behavioural disturbances, taste disturbances, cataract, glaucoma.

Generic Symbicort (Foracort Inhaler) - More Details

For more details please read the Prescription Information or watch the presentation below:

Monday 17 November 2014

Treatment of Cancer, Autoimmune diseases and Lymphoma using Generic Rheumatrex

What are Autoimmune Diseases?

Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. Your body's immune system protects you from disease and infection. But in case of patients with an autoimmune disease, the immune system can't tell the difference between healthy body tissue and antigens and consequently the immune system attacks healthy cells in the body.
The treatment of autoimmune diseases is typically with immunosuppression-medication that decreases the immune response.

Generic Rheumatrex (Neotrexate Tablets) – Product Information

Generic Rheumatrex (Neotrexate Tablets), an antimetabolite and antifolate drug. is used in treatment of cancer, neoplastic diseases, severe psoriasis (a skin disease which is characterised by red, scaly patches on some areas of the body), autoimmune diseases, ectopic pregnancy, Eczema, Lymphoma, Trophoblastic Disease and adult rheumatoid arthritis (Disease in which the body attacks its own joints).
The active ingredient present in Generic Rheumatrex is Methotrexate.
Methotrexate is available as Neotrexate, Rheumatrex, Trexall, MTX, Amethopterin and generic Methotrexate. Neotrexate Tablets (Generic Rheumatrex) are manufactued by GlaxoSmithKline India

Generic Rheumatrex (Neotrexate Tablets) - Contraindications

Generic Rheumatrex (Neotrexate Tablets) is contraindicated in patients with a known hypersensitivity to Methotrexate or to any component of this medication. It is also contraindicated in pregnant women and nursing mothers.
Methotrexate (Neotrexate Tablets) is also contraindicated in patients with alcoholism, alcoholic liver disease or other chronic liver disease those who have overt or laboratory evidence of immunodeficiency syndromes as well as those who have preexisting blood dyscrasias, such as bone marrow hypoplasia, leukopenia, thrombocytopenia or significant anemia.

Generic Rheumatrex (Neotrexate Tablets) - Dosage

The dosage of Generic Rheumatrex (Neotrexate Tablets) is different for different diseases and treatments. The adult dosage for some indications is given below:
Choriocarcinoma and similar trophoblastic diseases:
Methotrexate is administered orally in doses of 15 to 30 mg daily for a five-day course. Such courses are usually repeated for 3 to 5 times as required, with rest periods of one or more weeks interposed between courses, until any manifesting toxic symptoms subside.
Adult Rheumatoid Arthritis:
Recommended Starting Dosage Schedules
1. Single oral doses of 7.5 mg once weekly.
2. Divided oral dosages of 2.5 mg at 12 hour intervals for 3 doses given as a course once weekly
Polyarticular-Course Juvenile Rheumatoid Arthritis:
The recommended starting dose is 10 mg/m2 given once weekly

Side Effects of Generic Rheumatrex Tablets (Methotrexate)

The most common side effects of Generic Rheumatrex Tablets (Methotrexate) include ulcerative stomatitis, leukopenia, nausea, and abdominal distress. Other commonly reported side effects are malaise, undue fatigue, chills and fever, dizziness and decreased resistance to infection.

Generic Rheumatrex (Neotrexate Tablets) - More Details

For more details please read the Prescription Information or watch the presentation below:

Saturday 15 November 2014

Treatment of Obsessions and Compulsions Using Generic Anafranil Tablets

Generic Anafranil (Clomipramine Hydrochloride Tablets)– Product Information

Generic Anafranil (Clomipramine Hydrochloride tablets) is used for the treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD). It is also used for the treatment of depressive states in adults including Major depressive disorder (MDD), Panic disorder with or without agoraphobia, Phobias and panic attacks, Body Dysmorphic Disorder, Depersonalization disorder, Trichotillomania, Cataplexy accompanying narcolepsy and Chronic painful conditions with or without organic disease.
The active ingredient present in Generic Anafranil (Clonil) is Clomipramine Hydrochloride.

Dosage And Administration

Clonil (Generic Anafranil) comes as an oral tablet in 10 mg, 25 mg and 50 mg dosage forms. The recommended Oral dosage of Generic Anafranil for adults is given below:
Treatment of Depression in Adults:
Clomipramine HCl (Clonil Tablets) therapy should be started at daily doses of 25 mg. Dosage may be increased by 25 mg increments, as tolerated, at 3 to 4 day intervals up to a total daily dose of 150 mg by the end of 2 weeks. Thereafter, the dose may be gradually increased over a period of several weeks to a maximum of 200 mg.
Treatment of Obsessive Compulsive Disorders in Adults:
Clomipramine HCl (Clonil Tablets) therapy in adult Obsessive Compulsive patients should be initiated at daily doses of 25 mg. Dosage may be increased by 25 mg increments, as tolerated, at 3 to 4 day intervals up to a total daily dose of 100 or 150 mg by the end of 2 weeks. Thereafter, the dose may be gradually increased over a period of several weeks to a maximum of 200 mg.

Clonil (Generic Anafranil) - Contraindications

Generic Anafranil (Clonil tablets) is contraindicated for patients with hypersensitivity to Clomipramine Hydrochloride or any of the inactive ingredients present in Clonil tablets.

Generic Anafranil Tablets - Warnings and Precautions

The risk of suicide is inherent in depression and may persist until significant remission occurs. This risk must be considered in all depressed patients.
Patients with depression may experience worsening of their depressive symptoms and/or the emergence of suicidal ideation and behaviours (suicidality) whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs.
When undergoing treatment with Generic Anafranil caution is required in patients with the following medical conditions:

  • Cardiovascular disorders, especially those with cardiovascular insufficiency, conduction disorders or arrhythmias
  • A history of increased intraocular pressure, narrow-angle glaucoma.
  • Disorders of micturition due to an impeded flow of urine (e.g. in diseases of the prostate).
  • A low convulsion threshold
  • Severe hepatic or renal diseases.
  • Tumours of the adrenal medulla in whom the medicine may provoke hypertensive crises.
  • Hyperthyroidism or concomitant treatment with thyroid preparations.
  • Chronic constipation, as tricyclic antidepressants may cause paralytic ileus, particularly in elderly and in bedridden patients.

Side Effects of Generic Anafranil Tablets

The common possible side effects of Generic Anafranil (Clonil tablets) with a frequency rate of 10% or more include:

  • Accommodation disorder
  • Blurred vision
  • Nausea
  • Dry mouth
  • Constipation
  • Fatigue
  • Weight gain
  • Increased appetite
  • Dizziness
  • Tremor
  • Headache
  • Myoclonus
  • Drowsiness
  • Somnolence
  • Restlessness
  • Vomiting
  • Diarrhea
  • Nervousness
  • Stuffy nose
  • Change in appetite or weight
  • Decreased memory or concentration
  • Decreased sexual ability
  • Micturition disorder
  • Sexual dysfunction (erectile dysfunction and loss of libido)
  • Hyperhidrosis (profuse sweating)
Some side effects of Generic Anafranil tablets may be serious. If you experience any of the following symptoms listed below, call your doctor immediately or get emergency medical treatment:
  • Uncontrollable shaking of a part of the body
  • Seizures
  • Fast, irregular, or pounding heartbeat
  • Difficulty urinating or loss of bladder control
  • Believing things that are not true
  • Hallucinations (seeing things or hearing voices that do not exist)
  • Eye pain
  • Shakiness
  • Difficulty breathing or fast breathing
  • Severe muscle stiffness
  • Unusual tiredness or weakness
  • Sore throat, fever, and other signs of infection

More Details on Clomipramine Hydrochloride Tablets (Generic Anafranil)

For more details on Generic Anafranil (Clomipramine Hydrochloride tablets) please read the Prescription Information or watch the presentation below.

Thursday 13 November 2014

Treatment of Arthritis, Bursitis and Tendinitis with Generic Indocin Capsules

What is Arthritis?

Arthritis is a degenerative joint disease, that involves inflammation of one or more joints. There are over 100 different types of arthritis. The most common form, osteoarthritis involves the breakdown of cartilage. The breakdown of cartilage can take place as as a result of trauma to the joint, infection of the joint, or age. This causes causes the bones to rub against each other, causing stiffness, swelling (inflammation), pain and loss of movement in the joint. Other forms of arthritis include rheumatoid arthritis, psoriatic arthritis, and related autoimmune diseases. Septic arthritis is caused by joint infection. The main complaint among individuals who suffer from arthritis is joint pain. The pain is usually localized to the joint affected and is due to inflammation that occurs around the joint, damage to the joint from disease, daily wear and tear of joint, muscle strains caused by forceful movements against stiff, painful joints and fatigue.

What is Tendinitis and Bursitis?

Tendinitis or bursitis often involves the shoulder, elbow, wrist, hip, knee and ankle. The pain caused by Bursitis and Tendinitis could be quite severe and is worse during movement.
What is tendinitis?
Tendons are cord-like structures located where a muscle narrows down to attach to a bone. The tendon is more fibrous and dense than the elastic, fleshy muscle. A tendon transmits the pull of the muscle to the bone to cause movement. Tendinitis (informally also tendonitis), means the inflammation of a tendon. Tendinitis is often very tender to the touch. The term tendinitis is reserved for tendon injuries that involve larger-scale acute injuries accompanied by inflammation. Generally tendinitis is referred to by the body part involved, such as Achilles tendinitis (affecting the Achilles tendon), or patellar tendinitis (jumper's knee, affecting the patellar tendon).
What is bursitis?
Bursitis is the inflammation of one or more bursae (small sacs) of synovial fluid in the body. The bursae rest at the points where internal functionaries, such as muscles and tendons, slide across bone. This small sac acts as a cushion between moving structures (bones, muscles, tendons or skin). Healthy bursae create a smooth, almost frictionless functional gliding surface making normal movement painless. If a muscle or tendon is pulling around a corner of a bone, or over a bone, a healthy bursa protects it from fraying and stress.
When bursitis occurs and a bursa is inflamed, movement relying upon the inflamed bursa becomes difficult and painful. Moreover, movement of tendons and muscles over the inflamed bursa aggravates its inflammation, perpetuating the problem. Muscle can also be stiffened.
Tendinitis can occur from a sudden intense injury. Most often, though, it results from a repeated, minor injury of that tendon. Doctors call this repetitive stress or overuse. Examples of such injuries are painting a ceiling for four hours or more, typing long hours, improper body position while using a keyboard, chopping, cutting or sawing may result in tendinitis or bursitis hours or days later. Tight clenching while using hand tools or while driving a long time, using a backhand, mainly single handed, in an early-season game of tennis ("tennis elbow") and wearing improper running shoes or not getting the proper training before sports are other examples.

Generic Indocin Capsules (Inmecin) – Product Information

Generic Indocin Capsules (Inmecin Capsules) is used to relieve moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
The active ingredient present in Generic Indocin Capsules is Indomethacin.
Indomethacin is marketed under trade names such as Inmecin,Indocid, Indocid Pda, Indocid Sr, Indocin, Rheumacin, Indocap, Indochron and several others.

Generic Indocin Capsules (Inmecin Capsules) - Contraindications

Generic Indocin Capsules (Inmecin Capsules) is contraindicated in patients with known hypersensitivity to indomethacin or any inactive ingredient present in Generic Indocin Capsules.
Inmecin Capsules (Generic Indocin) should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic/anaphylactoid reactions to NSAIDs have been reported in such patients. Indomethacin (Generic Indocin) is also contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.

Generic Indocin (Inmecin Capsules) - Dosage

The recommended adult Oral dosage of Generic Indocin(Inmecin Capsules) for adults is given below:
Moderate To Severe Rheumatoid Arthritis Including Acute Flares Of Chronic Disease, Moderate To Severe Ankylosing Spondylitis, And Moderate To Severe Osteoarthritis
Recommended Adult Dosage: Indomethacin capsules 25 mg twice a day or three times a day If this is well tolerated, increase the daily dosage by 25 or by 50 mg, if required by continuing symptoms, at weekly intervals until a satisfactory response is obtained or until a total daily dose of 150 to 200 mg is reached.
Acute Painful Shoulder (Bursitis And/Or Tendinitis)
The initial adult doseage is 75 to 150 mg daily in 3 or 4 divided doses. Generic Indocin (Inmecin capsules) should be discontinued after the signs and symptoms of inflammation have been controlled for several days. The usual course of therapy is 7 to 14 days.
Acute Gouty Arthritis
The adult dosage is 50 mg of Generic Indocin capsules thrice a day until pain is tolerable. The dose should then be rapidly reduced to complete cessation of the drug. Definite relief of pain has been reported within 2 to 4 hours. Tenderness and heat usually subside in 24 to 36 hours, and swelling gradually disappears in 3 to 5 days.

Side Effects of Generic Indocin Capsules (Indomethacin)

The most common side effects reported in patients treated with Generic Indocin are headache, dizziness, light-headedness, changes in mood including depression, tiredness, spinning sensation (vertigo), stomach upset including nausea (feeling sick), vomiting, abdominal pain, loss of appetite, constipation, diarrhoea, ringing ears or other hearing disturbances flushing, and sweating.
The rare but serious side effects of Indomethacin include severe stomach pain or tenderness, eye problems including blurred vision, irregular heart beat, bleeding or bruising more frequently, jaundice (symptoms include yellowing of the skin and eyes), hepatitis, rash, itchy skin, loss of hair, unusual weight gain, swelling of ankles or legs, signs of anaemia such as tiredness, being short of breath, looking pale, changes in the frequency that you urinate or difficulty passing urine, dark coloured or cloudy urine.

Generic Indocin Capsules - More Details

For more details on please read the Prescription Information or watch the presentation below:

Treatment of COPD using Generic Spiriva Inhaler

Generic Spiriva Inhaler (Tiova Inhaler) – Product Information

Tiova Inhaler, manufactured by Cipla Ltd. (Generic Spiriva) is a long-acting, 24 hour, anticholinergic bronchodilator which is used to for the long-term, once-daily, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease(COPD) which includes bronchitis and emphysema.
Generic Spiriva works by relaxing the muscles around the airways so that they open up and enables patients to breathe more easily.
The active ingredient present in Generic Spiriva Inhaler is Tiotropium Bromide.
Tiotropium Bromide Inhaler is marketed under trade names such as Spiriva and Tiova. It is also available as a dry inhalation powder under the same brand names.

Generic Spiriva Inhaler - Contraindications

Generic Spiriva Inhaler (Tiova Inhaler) is contraindicated in patients with a hypersensitivity to to Tiotropium, Ipratropium, or any inactive component of this medication.

Generic Spiriva Inhaler (Tiova Inhaler) - Dosage

Tiova Inhaler (Generic Spiriva ) comes as an inhaler with 120 metered doses in 9 mcg dosage forms.The recommended adult Oral dosage of Generic Spiriva for adults is given below:
Dosage for Treatment of Adults
The maximum dose of Tiotropium Bromide is 18 mcg (2 puffs of Tiova Inhaler) which is administered by the inhalation device.

Generic Spiriva Inhaler (Tiova Inhaler) - Warnings and Precautions

The warnings and precautions to be taken when undergoing treatment with Tiova Inhaler are given below:

  • Not for emergency use: Generic Spiriva Inhaler is not for acute use, i.e., not a rescue medication
  • Immediate hypersensitivity reactions: Discontinue Generic Spiriva at once and consider alternatives if immediate hypersensitivity reactions, including angioedema, bronchospasm, or anaphylaxis, occur.
  • Paradoxical bronchospasm: Discontinue Generic Spiriva and consider other treatments if paradoxical bronchospasm occurs.
  • Worsening of narrow-angle glaucoma may occur. Use with caution in patients with narrow-angle glaucoma and instruct patients to consult a physician immediately if this occurs.
  • Worsening of urinary retention may occur. Use with caution in patients with prostatic hyperplasia or bladder-neck obstruction and instruct patient to consult a physician immediately if this occurs.

Side Effects of Generic Spiriva Inhaler (Tiova Inhaler)

The common possible side effects reported in patients treated with Tiova Inhaler (Generic Spiriva) include pharyngitis, cough, dry mouth and/or throat irritation and sinusitis . Rarely occuring side effects that occur in less than 0.1% of patients undergoing treatment are urinary retention, constipation, acute angle closure glaucoma, palpitations (notably supraventricular tachycardia and atrial fibrillation) and/or allergy (rash, angioedema, anaphylaxis).

Generic Spiriva Inhaler (Tiova Inhaler) - More Details

For more details please read the Prescription Information or watch the presentation below:

Tuesday 11 November 2014

Treatment of Seasonal or Perennial Allergic Rhinitis Using Generic Rhinocort Aqua Nasal Spray

What is Allergic Rhinitis?

Allergic Rhinitis is an allergic inflammation of the nasal airways which occurs when an allergen, such as pollen, dust or particles of shed skin and hair of animals is inhaled by an individual with a sensitized immune system.
As soon as such a person comes into contact with an allergen, one or more of the following is noticed: Itchy nose, mouth, eyes, throat, skin,and face, Fatigue, Sore throat, Dry cough, Stuffy, runny nose , Problems with smell, hearing, and taste, Headaches, facial pain or pressure, Swollen eyelids, Sneezing and Red, itchy, and watery eyes. Medicines such as nasal corticosteroid sprays may help control allergy symptoms.

Generic Rhinocort Aqua Nasal Spray (Budenase Nasal Spray) – Product Information

Generic Rhinocort Aqua Nasal Spray (Budenase Nasal Spray) a corticosteroid, is used for the Treatment of seasonal or perennial allergic rhinitis , nasal congestion, sneezing and runny nose due to allergies and asthma in adults and children 6 years and above.
The active ingredient present in Generic Rhinocort Aqua Nasal Spray is Budesonide. Each spray delivers Budesonide IP 100 mcg.
Budesonide nasal spray is available as Rhinocort, Budenase, Rhinosol, Pulmicort, Budicort, Symbicort, and Noex.

Generic Rhinocort Aqua Nasal Spray (Budenase Nasal Spray) - Contraindications

Generic Rhinocort Aqua is contraindicated in patients with a known hypersensitivity to or to any component of this medication

Generic Rhinocort Aqua Nasal Spray (Budenase Nasal Spray) - Dosage

The recommended starting dosage of Budenase Nasal Spray (Budesonide Nasal Spray) for adults and children 6 years of age and older is administered as one spray of Generic Rhinocort Aqua Nasal Spray per nostril once daily.

Side Effects of Generic Rhinocort Aqua Nasal Spray

The most common side effects reported in patients treated with Generic Generic Rhinocort Aqua Nasal Spray (Budenase Nasal Spray) with an incidence rate of 2% or more are epistaxis, pharyngitis, bronchospasm, coughing, nasal irritation.
In addition, Budesonide was found by researchers to potentially cause a permanent small decrease in height in certain children taking the medicine.

Generic Rhinocort Aqua Nasal Spray - More Details

For more details on Generic Rhinocort Aqua (Budenase Nasal Spray) please read the Prescription Information or watch the presentation below:

Monday 10 November 2014

Treatment of Breast cancer Using Generic Femara Tablets

Generic Femara (Letrozole Tablets) – Product Information

Generic Femara tablets (Letromina, manufactured by Alpha Pharma India) an oral non-steroidal aromatase inhibitor, are used for the treatment of hormonally-responsive breast cancer in post-menopausal women i.e. women who no longer have periods, either because of their natural age or following surgery or chemotherapy.
Generic Femara tablets are used for adjuvant treatment of postmenopausal women with hormone receptor positive early breast cancer. It is also used for treatment of extended adjuvant treatment of early breast cancer in post menopausal women who have received between 4.5 and 6.0 years prior standard adjuvant Tamoxifen therapy, First-line treatment in postmenopausal women with advanced breast cancer and treatment of advanced breast cancer in women with natural or artificially induced postmenopausal status, who have previously been treated with antioestrogens.
The active ingredient present in Generic Femara tablets is Letrozole.
Letrozole is marketed under trade names such as Femara, Fertolet and Letromina.

Dosage And Administration

Letromina (Generic Femara) comes as an oral tablet in 2.5 mg dosage forms. The recommended adult Oral dosage of Generic Femara tablets (Letromina) is given below:
Dosage for Treatment of Adults
The recommended dose of Letromina tablets is 2.5 mg once daily. In the adjuvant and extended adjuvant setting, treatment with Generic Femara (Letrozole tablets) should continue for 5 years or until tumour relapse occurs, whichever comes first. In patients with metastatic disease, treatment with Letrozole tablets should continue until tumour progression is evident.

Letrozole Tablets (Letromina Tablets) - Contraindications

Generic Femara® (Letromina tablets) is contraindicated in patients with known hypersensitivity to Letrozole or any of its inactive ingredients.
Generic Femara is contraindicated in women of premenopausal endocrine status (i.e. Women who still have periods) . It is also contraindicated in women who are pregnant or breast-feeding.

Generic Femara Tablets (Letromina Tablets) - Warnings and Precautions

The warnings and precautions to be taken when undergoing treatment with Generic Femara is given below:

  • Decreases in bone mineral density may occur. Consider bone mineral density monitoring.
  • Increases in total cholesterol may occur. Consider cholesterol monitoring.
  • Fatigue, dizziness and somnolence may occur. Exercise caution when operating machinery

Side Effects of Generic Femara tablets (Letromina)

The most common possible side effects of Generic Femara tablets (Letromina) occuring in 20% or more of the patients undergoing treatment were hot flashes, arthralgia (joint pain), flushing, asthenia, edema, arthralgia, headache, dizziness, hypercholesterolemia, increased sweating, bone pain and musculoskeletal problems.

More Details on Letrozole Tablets

For more details on Generic Femara (Letrozole tablets) please read the Prescription Information or watch the presentation below.

Friday 7 November 2014

Asthma Prevention Using Generic Beclovent Inhaler

Generic Beclovent Inhaler (Beclate Inhaler) – Product Information

Generic Beclovent Inhaler (Beclate Inhaler, manufactured by Cipla) is used to prevent symptoms such as wheezing, shortness of breath, coughing, and chest tightness caused by asthma and other lung diseases in patients 5 years of age and older. Asthma causes the lining of thelungs to become inflamed (red and swollen), making it difficult to breathe. Beclomethasone Dipropionate works by reducing the inflammation in your airways. This helps to improve the patient's condition and to prevent asthma attacks from occurring. It is also used in the maintenance treatment of asthma as well as for asthma patients who require systemic corticosteroid administration to reduce or eliminate the need for the systemic corticosteroids.
The active ingredient present in Generic Beclovent Inhaler is Beclometasone Dipropionate.
Beclometasone Dipropionate inhaler is also marketed under trade names such as Beclovent Inhaler, Vanceril, Clenil, Asmabec Clickhaler, Beclate Inhaler, Clenil Modulite, Qvar and Easyhaler Beclometasone Dipropionate. It is also marketed as a nasal spray (e.g. Beconase, alanase, Vancenase) or nasal aerosol (e.g. Qnasl).

Dosage And Administration

Generic Beclovent Inhaler (Beclate Inhaler) comes as an aerosol to inhale by mouth. Each actuation delivers Beclomethasone Dipropionate IP 100 mcg suspended in CFC-free propellant in case of a BECLATE-100 Inhaler and 200 mcg in case of a BECLATE-200 Inhaler . Beclate Inhaler is manufactured by Cipla Ltd. Mumbai, India. Each Beclate inhaler contains 200 metered doses. The recommended adult dosage of Generic Beclovent Inhaler for adults is given below:
Adults and children over 12 years of age:-
Patients should be given a starting dose of inhaled Beclometasone Dipropionate which is appropriate for the severity of their disease based on the following guidance:
Mild asthma: 200 to 600mcg per day in divided doses.
Moderate asthma: 600 to 1000mcg per day in divided doses.
Severe asthma: Up to 1000mcg per day in divided doses.
The dose may then be adjusted until control is achieved or reduced to the minimum effective dose according to the individual response.
Children over 7 years of age:-
Up to 200mcg per day in divided doses.
Children should be given a starting dose of inhaled beclometasone dipropionate which is appropriate for the severity of their disease. The dose may then be adjusted until control is achieved or reduced to the minimum effective dose according to the individual response.

Generic Beclovent Inhaler (Beclate Inhaler) - Contraindications

Generic Beclovent Inhaler is contraindicated for patients with hypersensitivity to Beclometasone Dipropionate or any of the inactive ingredients present in Beclate Inhaler.
Generic Beclovent Inhaler is also contraindicated in the primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures are required.

Generic Beclovent Inhaler (Beclate Inhaler) - Warnings and Precautions

When undergoing treatment with Generic Beclovent Inhaler the below mentioned precautions have to be noted:

  • Patients have to be monitored periodically for signs of adverse effects on the oral cavity as Candida albicans infection of the mouth and throat may occur.
  • Generic Beclovent Inhaler should not be used for relief of acute symptoms.
  • There is a risk of impaired adrenal function when transferring patients from systemic corticosteroids.
  • There exists a risk of potential worsening of existing tuberculosis, fungal, bacterial, viral, or parasitic infection; or ocular herpes simplex infections. More serious or even fatal course of chickenpox or measles can occur in susceptible patients.
  • Bronchospasm, (Paradoxical Bronchospasm) with an immediate increase in wheezing, may occur after dosing.
  • Hypersensitivity reactions, such as urticaria, angioedema, rash, and bronchospasm may occur. Discontinue Beclate Inhaler in case such reactions occur.
  • Hypercorticism and adrenal suppression may occur with very high dosages or at the regular dosage in susceptible individuals. In case such changes occur, discontinue Beclate Inhaler slowly.
  • Growth of pediatric patients has to be monitored for adverse effects of Generic Beclovent Inhaler.
  • Patients with major risk factors for decreased bone mineral content have to be monitored.
  • Patients with change in vision or with a history of increased intraocular pressure, glaucoma, and/or cataracts have to be closely monitored.

Side Effects of Generic Beclovent Inhaler (Beclate Inhaler)

The common side effects reported in patients treated with Generic Beclovent Inhaler (Beclate Inhaler) include headache, pharyngitis, oral symptoms (inhalation route), occasional cough upon inhalation, and sinusitis. Deposition on the tongue and throat may promote oral candidiasis, which appears as a white coating, possibly with irritation (usually prevented by rinsing the mouth with water after using the inhaler). Other side effects may rarely include: a smell similar to burning plastic, unpleasant taste, hoarseness or nasal congestion, pain or headache and visual changes. Allergic reactions may occur, but rarely.

More Details

For more details on Generic Beclovent please watch the presentation below.

Treatment of Epilepsy and Bipolar Disorder using Generic Lamictal Tablets

Generic Lamictal Tablets (Lametec) – Product Information

Generic Lamictal (Lametec tablets, manufactured by Cipla Ltd.) is an anticonvulsant medication used in the treatment of epilepsy and bipolar disorder. It works by decreasing abnormal electrical activity in the brain.For epilepsy, Lametec Tablets (Generic Lamictal) is used in partial or generalised seizures including Lennox-Gastaut Syndrome. It is also used off-label as an adjunct in treating clinical depression.
The active ingredient present in Generic Lamictal tablets is Lamotrigine.
Lamotrigine is marketed under trade names such as Lamictal ®, Lamictal® CD, Lamictal® ODT, Lamictal® XR and Lametec DT .

Dosage And Administration

Lametec DT (Generic Lamictal) comes as an oral tablet in 25 mg, 50 mg and 100 mg dosage forms. The recommended adult Oral dosage of Generic Lamictal is given below:
Dosage for Treatment of Epilepsy Add-On Therapy In Adults (over 12 years of age)
In patients taking valproate with/without any other anti-epileptic drug (AED), the initial Generic Lamotrigine Tablets (Lametec) dose is 25 mg every alternate day for two weeks, followed by 25 mg once a day for two weeks. Thereafter, the dose should be increased by a maximum of 25-50 mg every 1-2 weeks until the optimal response is achieved. The usual maintenance dose to achieve optimal response is 100-200 mg/day given once a day or in two divided doses.
In those patients taking enzyme inducing AEDs or other medications that induce lamotrigine glucuronidation with/without other AEDs (except valproate), the initial Generic Lamotrigine Tablets (Lametec) dose is 50 mg once a day for two weeks, followed by 100 mg/day given in two divided doses for two weeks.
Thereafter, the dose should be increased by a maximum of 100 mg every 1-2 weeks until the optimal response is achieved. The usual maintenance dose to achieve optimal response is 200- 400 mg/day given in two divided doses. Some patients have required 700 mg/day of lamotrigine to achieve the desired response.
Dosage for Bipolar Disorder Adults (18 years of age and over):
Because of the risk of rash, the initial dose and subsequent dose escalation should not be exceeded. Lamotrigine is recommended for use in bipolar patients at risk for a future depressive episode. The recommended initial adult dosage of Lametec DT is 25 mg once daily for 2 weeks, followed by 50 mg once daily for 2 weeks.
For Patients NOT TAKING Carbamazepine, Phenytoin, Phenobarbital, Primidone, or Valproate
Weeks 1 and 2 25 mg daily
Weeks 3 and 4 50 mg daily
Week 5 100 mg daily
Week 6 and 7 200 mg daily

Generic Lamictal Tablets (Lametec) - Contraindications

Generic Lamictal is contraindicated for patients with hypersensitivity to or Lamotrigine any of the inactive ingredients present in Generic Lamictal (Lametec DT)

Generic Lamictal Tablets (Lametec) - Warnings and Precautions

The following precautions have to be taken when undergoing treatment with Generic Lamictal tablets:

  • Life threatening serious rash and/or rash-related death may result
  • Fatal or life-threatening hypersensitivity reaction: Multiorgan hypersensitivity reactions, also known as drug reaction with eosinophilia and systemic symptoms, may be fatal or life threatening. Early signs may include rash, fever, and lymphadenopathy. These reactions may be associated with other organ involvement, such as hepatitis, hepatic failure, blood dyscrasias, or acute multiorgan failure. Generic Lamictal Tablets should be discontinued if alternate cause for this reaction is not found.
  • Blood dyscrasias (e.g., neutropenia, thrombocytopenia, pancytopenia May occur, either with or without an associated hypersensitivity syndrome.
  • Suicidal behavior and ideation.
  • Clinical worsening, emergence of new symptoms, and suicidal ideation/behaviors may be associated with treatment of bipolar disorder. Patients should be closely monitored, particularly early in treatment or during dosage changes.
  • Aseptic meningitis reported in pediatric and adult patients.
  • Medication errors involving Generic Lamictal (Lametec DT) have occurred. In particular the names Generic Lamictal or lamotrigine can be confused with names of other commonly used medications. Medication errors may also occur between the different formulations of Lametec.

Side Effects of Generic Lamotrigine Tablets (Lametec)

The common adverse effects (incidence 10% or greater) reported in patients treated with Lamotrigine (Lametec DT Tablets) in adult epilepsy clinical studies were dizziness, headache, diplopia, ataxia, nausea, blurred vision, somnolence, rhinitis, and rash.
Additional adverse reactions (incidence 10% or greater) reported in children in epilepsy clinical studies included vomiting, infection, fever, accidental injury, pharyngitis, abdominal pain, and tremor. Most common adverse effects with an incidence rate 5% or more in adult bipolar clinical studies were nausea, insomnia, somnolence, back pain, fatigue, rash, rhinitis, abdominal pain, and xerostomia.

More Details on Generic Lamotrigine Tablets (Lametec)

For more details on Lamotrigine Tablets (Lametec) please read the Prescription Information or watch the presentation below.

Thursday 6 November 2014

Treatment of Postherpetic Neuralgia Using Generic Neurontin Capsules

Generic Neurontin Capsules (Gabantin) – Product Information

Generic Neurontin Capsules (Gabantin manufactured by Sun Pharma) is used for the treatment of postherpetic neuralgia in adults. Generic Neurontin is also used as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy. There are, however, concerns regarding the quality of the research on its use to treat migraines, bipolar disorders, and pain.
The active ingredient present in Generic Neurontin is Gabapentin.
Gabantin is supplied as capsules containing 300 mg of the active ingredient Gabapentin.

Dosage And Administration

Gabantin (Generic Neurontin) comes as an oral capsule in 300 mg and 100 mg dosage forms. Generic Neurontin is given orally with or without food. The recommended dosage of Generic Neurontin for adults is given below:
Dosage for Treatment of Postherpetic Neuralgia in Adults:
In adults with postherpetic neuralgia, Gabantin therapy may be started as a single 300-mg dose on Day 1, 600 mg/day on Day 2 (300 mg twice a day), and 900 mg/day on Day 3 (300 mg thrice a day). The dose can subsequently be increased as needed for pain relief upto to a daily dose of 1800 mg (600 mg thrice a day).
Dosage for Treatment of Epilepsy :
Generic Neurontin (Gabantin Capsules) is recommended for add on therapy in patients 3 years of age and older. For adult patients (age 12 and above) the effective dose of Gabapentin is 900 to 1800 mg/day and given in divided doses (three times a day). The starting dose of Gabantin Capsules is 300 mg three times a day. If required, the dose may be increased to up to 1800 mg/day using 3 divided doses.

Generic Neurontin Capsules (Gabantin) - Contraindications

Generic Neurontin Capsules (Gabantin) is contraindicated for patients with a hypersensitivity to Gabapentin or any of the inactive ingredients present in Gabantin capsules.

Generic Neurontin Capsules (Gabantin) - Warnings and Precautions

The warnings and precautions when using Generic Neurontin Capsules (Gabantin) are given below:

  • Drug Reaction with Eosinophilia and Systemic Symptoms (Multiorgan hypersensitivity): Discontinue Generic Neurontin Capsules.
  • Driving impairment: warn patients not to drive until they have gained sufficient experience with Generic Neurontin Capsules to assess whether it will impair their ability to drive.
  • Somnolence/Sedation and Dizziness: Gabantin may impair the patient's ability to operate complex machinery (5.3) Increased seizure frequency may occur in patients with seizure disorders if Generic Neurontin Capsules (Gabantin)is abruptly discontinued
  • Suicidal Behavior and Ideation: monitor for suicidal thoughts and behavior
  • Neuropsychiatric Adverse Reactions in Children 3-12 Years of Age: monitor for such events

Side Effects of Generic Neurontin (Gabantin Capsules)

The common possible side effects reported in patients treated with Generic Neurontin (Gabantin Capsules) in adults, were dizzines, somnolence, and peripheral edema.

More Details

For more details on Generic Neurontin please read the Prescription Information or watch the presentation below.

Tuesday 4 November 2014

Treatment of Asthma Using Generic Foradil Aerolizer

Generic Foradil Aerolizer (Foratec Rotacaps) – Product Information

Generic Foradil Aerolizer (Foratec Rotacaps, manufactured by Cipla Ltd.) is a Long-acting beta2-adrenergic agonist (LABA) used for the treatment of asthma in patients 5 years and above as an add-on to a long-term asthma control medication such as an inhaled corticosteroid. It is also used for prevention of exercise-induced bronchospasm (EIB) in patients 5 years and above and for the maintenance treatment of bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD).
The active ingredient present in Generic Foradil Aerolizer is Formoterol Fumarate.
Formoterol Fumarate is marketed under trade names such as Foradil Aerolizer, Oxeze turbuhaler, Foradil, Foradile, Oxeze, Oxis, Atock, Formoterol Fumarate and Formoterol.

Dosage And Administration

Generic Foradil Aerolizer comes as an Inhalation Powder in 12 mcg dosage forms. The recommended adult Oral dosage of Generic for adults is given below:
Treatment of asthma in patients 5 years and above:
Inhalation of one capsule every 12 hours in addition to concomitant treatment with a long-term control medication such as an inhaled corticosteroid.
Exercise-Induced Bronchospasm (EIB):
Inhalation of one capsule at least 15 minutes before exercise. Additional doses should not be used for 12 hours.
Maintenance treatment of bronchoconstriction in patients with COPD:
Inhalation of one capsule every 12 hours

Generic Foradil Aerolizer (Foratec Rotacaps) - Contraindications

Generic Foradil Aerolizer is contraindicated in patients with a hypersensitivity to Formoterol Fumarate or to any other components of this medicine.
Generic Foradil Aerolizer (Foratec Rotacaps) is also contraindicated for treatment of Asthma without concomitant use of a long term asthma control medication such as an inhaled corticosteroid.

Generic Foradil Aerolizer (Foratec Rotacaps) – Warnings and Precautions

When undergoing treatment with Generic Foradil Aerolizer (Formoterol Fumarate Inhalation Powder) the following has to be kept in mind:

  • Asthma-related deaths and asthma-related hospitalizations: LABA increase the risk. Generic Foradil Aerolizer has to be prescribed for asthma only as concomitant therapy with a long-term control medication such as an inhaled corticosteroid.
  • Deterioration of asthma and acute episodes: Do not initiate treatment with Foratec Rotacaps during acutely deteriorating asthma. Do not use to treat acute symptoms.
  • Corticosteroids: Not a substitute for corticosteroids. Corticosteroids should not be stopped or reduced when treatment with Foratec Rotacaps (Generic Foradil Aerolizer) is initiated.
  • Use with additional long-acting beta2-agonist: Do not use in combination because of risk of overdose.
  • Paradoxical bronchospasm: Discontinue Generic Foradil Aerolizer and institute alternative therapy if paradoxical bronchospasm occurs.
  • Patients with cardiovascular or central nervous system disorders: Use with caution because of beta-adrenergic stimulation.
  • Coexisting conditions: Use with caution in patients with convulsive disorders, thyrotoxicosis, diabetes mellitus, ketoacidosis, aneurysm, and pheochromocytoma.
  • Metabolic effects: Be alert to hypokalemia and hyperglycemia.

Side Effects of Generic Foradil Aerolizer (Formoterol Fumarate Inhalation Powder)

The common possible side effects reported in patients treated with Generic Foradil Aerolizer (Foratec Rotacaps) include trembling or shakiness, muscle aching or cramps, palpitations (feeling that your heartbeat is unusually fast or irregular), headache, dizziness, feeling anxious, nervous or upset, being unable to sleep, sore mouth or throat from inhaling the powder in the capsule, changed sense of taste, nausea (feeling sick), dry mouth,excessive thirst, frequent urination and tiredness over an extended period of time

More Details about Generic Foradil Aerolizer (Formoterol Fumarate Inhalation Powder)

For more details on Generic Foradil Aerolizer please read the Prescription Information or watch the presentation below.

Hormone Replacement Therapy Using Generic Ovestin Cream

Generic Ovestin Cream (Evalon Vaginal Cream) – Product Information

Generic Ovestin Cream (Evalon Vaginal Cream) is used in Hormone Replacement Therapy (HRT) in women. It contains oestriol. Oestriol is one of the female hormones, called oestrogens, that is naturally produced in women. During and after the change of life (menopause) the oestrogen production decreases. This decrease may lead to hot flushes, vaginal irritation, recurrent urinary tract infections and urinary incontinence. Ovestin Cream can be prescribed for the loss of oestrogen production.
The active ingredient present in Generic Ovestin Cream is Estriol (Oestriol). Estriol (Oestriol) is particularly effective in the treatment of urogenital symptoms. In case of atrophy of the lower urogenital tract oestriol induces the normalization of the urogenital epithelium and helps to restore the normal microflora and the physiological pH in the vagina.

Dosage And Administration

Generic Ovestin Cream comes as a cream containing 1 mg Estriol for every 1 gm of the cream. The recommended dosage of Generic Ovestin Cream for adults is given below:

Atrophy of the Lower Urogenital Tract:
1 application (0.5g Generic Ovestin Cream) per day for the first weeks, followed by a gradual reduction, based on relief of symptoms, until a maintenance dosage (e.g. 1 application twice a week) is reached.

Pre- and Post-Operative Therapy in Postmenopausal Women Undergoing Vaginal Surgery:
1 application (0.5g Generic Ovestin Cream) per day in the 2 weeks before surgery; 1 application twice a week in the 2 weeks after surgery.

A Diagnostic Aid in case of a Doubtful Atrophic Cervical Smear:
1 application (0.5g Generic Ovestin Cream) on alternate days in the week before taking the next smear.

Generic Ovestin Cream (Evalon Vaginal Cream) - Contraindications

Generic Ovestin Cream (Evalon Vaginal Cream) is contraindicated for patients with hypersensitivity to Estriol or any of the inactive ingredients present in Generic Ovestin cream .
It is also contraindicated in the following cases:

  • you have had angina or a heart attack (myocardial infarction)
  • you have had a blood clot (thrombosis)
  • you have had breast cancer or suspect that you have breast cancer or you have had cancer of other sex organs such as cancer of the womb lining or ovary
  • you have vaginal bleeding that has not been explained by your doctor
  • you have excessive thickening of the womb lining
  • you have had a liver disease, and your liver is still not working properly
  • you have a rare blood problem called 'porphyria'

Generic Ovestin Cream - Warnings and Precautions

In case Generic Ovestin Cream (Evalon Vaginal Cream) is used for the treatment of postmenopausal symptoms, HRT should only be initiated for symptoms that adversely affect quality of life.
In all cases, a careful appraisal of the risks and benefits should be undertaken at least annually and HRT should only be continued as long as the benefit outweighs the risk.

Side Effects of Generic Ovestin Cream (Evalon Vaginal Cream)

The common side effects reported in patients treated with Generic Ovestin Cream (Evalon Vaginal Cream) include nausea and vomiting, breast tenderness or pain in the breasts, vaginal bleeding or spotting during or on withdrawal of therapy, excessive production of cervical mucous, headache, application site irritation and pruritus.

More Details about Generic Ovestin Cream

For more details on Generic Ovestin Cream please read the Prescription Information or watch see the presentation below.

Monday 3 November 2014

Treatment of Worm Infections Using Generic Vermox Tablets

Mebendazole Tablets (Generic Vermox) – Product Information

Mebendazole Tablets (Generic Vermox) is used to treat certain types of worm infections in the gut such as Enterobius vermicularis (pinworm), Trichuris trichiura (whipworm), Ascaris lumbricoides (common roundworm), Ancylostoma duodenale (common hookworm), Necator americanus (American hookworm) in single or mixed infections. Generic Vermox (Mebendazole)works by inhibiting the formation of the worms’ microtubules and causes the worms’ glucose depletion.
The active ingredient present in Generic Vermox Tablets is Mebendazole.
Mebendazole is a broad-spectrum anthelmintic available as chewable tablets, each containing 100 mg of Mebendazole. Mebendazole is marketed under trade names such as Vermox, Mebex and other brands.

Dosage And Administration

Generic Vermox (Mebendazole) comes as an oral tablet in 100 mg dosage forms . The recommended adult Oral dosage of Generic Vermox (Mebex) for adults is given below:
Treatment of Pinworms (Adult Dosage):
Mebex Dosage for treatment of pinworms is 100 mg taken once. This dose is repeated two weeks later if the infestation has not cleared up.
Treatment of Whipworm, Common Roundworm and Hookworm (Adult Dosage):
Oral dosage for treatment of whipworm, common roundworm and hookworm in adults is 100 mg twice a day for 3 consecutive days.
Treatment of Whipworm, Common Roundworm and Hookworm (Children 2 to 5 years):
Oral dosage for treatment of whipworm, common roundworm and hookworm in children more than 2 years of age and below 5 yrs of age and below 18 kg weight is one 100 mg tablet in the morning for three consecutive days.

Generic Vermox (Mebex Tablets) - Contraindications

Generic Vermox (Mebex tablets) are contraindicated in patients with hypersensitivity to Mebendazole or any of the inactive ingredients present in Mebex tablets.

Generic Vermox (Mebex Tablets) - Warnings and Precautions

When undergoing treatment with Generic Vermox tablets risk/ benefit analysis should be considered for the following:
Crohn's ileitis or ulcerative colitis
Generic Vermox may increase absorption and toxicity of mebendazole, especially in high dose therapy.
Caution is advised for use in patients with hepatic impairment since this condition may prolong half-life and drug accumulation

Side Effects of Generic Vermox (Mebendazole Tablets)

Mebendazole tablets (Generic Vermox) is relatively free of toxic side effects or adverse reactions. The common possible side effects reported in patients treated with Generic Vermox (Mebex Tablets) include diarrhoea, vomiting, and/or transient abdominal pain. Rash, slight headache, fever, dizziness, urticaria and angioedema have been observed on rare occasions.

More Details on Mebendazole Tablets (Generic Vermox)

For more details on Generic Vermox (Mebex tablets) please read the Prescription Information or watch the presentation below.

Treatment of Crohn's Disease Using Generic Entocort Capsules

Generic Entocort Capsules (Budez CR) – Product Information

Budesonide capsules (Generic Entocort capsules) is used for the treatment of patients with mild to moderate Crohn's disease affecting the ileum and/or the ascending colon as well as maintenance of remission (for up to 3 months) of Crohn's disease (mild-to-moderate) involving the ileum and/or ascending colon. Budesonide assists in the induction of remission in patients with active ulcerative colitis.
The active ingredient present in Generic Entocort capsules (Budez CR) is Budesonide.
Budesonide is marketed under trade names such as Uceris, Entocort EC and Budez CR.

Dosage And Administration

Generic Entocort (Budez CR capsules) comes as an oral capsule in 3 mg dosage form. The recommended adult oral dosage of Generic Entocort is given below:
Adult Dosage (Generic Entocort):
The recommended daily dose of Budez CR for induction of remission is 9 mg, administered once daily for up to eight weeks. The capsules should be taken in the morning before breakfast.

Generic Entocort Capsules (Budez CR) - Contraindications

Generic Entocort Capsules are contraindicated in patients with hypersensitivity to Budesonide or any of the inactive ingredients present in Budez CR tablets.

Generic Entocort Capsules (Budez CR) - Interactions

Simultaneous oral administration of ketoconazole (a known inhibitor of CYP3A4 activity in the liver and in the intestinal mucosa) caused an eight-fold increase of the systemic exposure to oral budesonide.
If treatment with inhibitors of CYP3A4 activity (such as ketoconazole, itraconazole, ritonavir, indinavir, saquinavir, erythromycin, etc.) is required, reduction of the budesonide dose should be considered.
After extensive intake of grapefruit juice (which inhibits CYP3A4 activity predominantly in the intestinal mucosa), the systemic exposure for oral budesonide increased about two times. Ingestion of grapefruit or grapefruit juice should be avoided in connection with budesonide administration.

Side Effects of Budesonide Capsules (Generic Entocort Capsules)

The common possible side effects reported in patients treated with Generic Entocort capsules include Headache, Respiratory Infection, Lightheadedness, Upset stomach, Nausea, Back Pain, Muscle cramps, Dyspepsia, Dizziness, Abdominal Pain, Flatulence, Vomiting, Fatigue, and Pain. In addition, should the following rare symptoms occur they should be reported immediately:

  • Difficulty breathing or swelling of the face
  • White patches in the throat, mouth, or nose
  • Irregular menstrual periods
  • Severe acne

More Details

For more details on Generic Budesonide capsules (Generic Entocort capsules) please please read the Prescription Information or watch the presentation below.