Thursday 6 November 2014

Treatment of Postherpetic Neuralgia Using Generic Neurontin Capsules

Generic Neurontin Capsules (Gabantin) – Product Information

Generic Neurontin Capsules (Gabantin manufactured by Sun Pharma) is used for the treatment of postherpetic neuralgia in adults. Generic Neurontin is also used as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy. There are, however, concerns regarding the quality of the research on its use to treat migraines, bipolar disorders, and pain.
The active ingredient present in Generic Neurontin is Gabapentin.
Gabantin is supplied as capsules containing 300 mg of the active ingredient Gabapentin.

Dosage And Administration

Gabantin (Generic Neurontin) comes as an oral capsule in 300 mg and 100 mg dosage forms. Generic Neurontin is given orally with or without food. The recommended dosage of Generic Neurontin for adults is given below:
Dosage for Treatment of Postherpetic Neuralgia in Adults:
In adults with postherpetic neuralgia, Gabantin therapy may be started as a single 300-mg dose on Day 1, 600 mg/day on Day 2 (300 mg twice a day), and 900 mg/day on Day 3 (300 mg thrice a day). The dose can subsequently be increased as needed for pain relief upto to a daily dose of 1800 mg (600 mg thrice a day).
Dosage for Treatment of Epilepsy :
Generic Neurontin (Gabantin Capsules) is recommended for add on therapy in patients 3 years of age and older. For adult patients (age 12 and above) the effective dose of Gabapentin is 900 to 1800 mg/day and given in divided doses (three times a day). The starting dose of Gabantin Capsules is 300 mg three times a day. If required, the dose may be increased to up to 1800 mg/day using 3 divided doses.

Generic Neurontin Capsules (Gabantin) - Contraindications

Generic Neurontin Capsules (Gabantin) is contraindicated for patients with a hypersensitivity to Gabapentin or any of the inactive ingredients present in Gabantin capsules.

Generic Neurontin Capsules (Gabantin) - Warnings and Precautions

The warnings and precautions when using Generic Neurontin Capsules (Gabantin) are given below:

  • Drug Reaction with Eosinophilia and Systemic Symptoms (Multiorgan hypersensitivity): Discontinue Generic Neurontin Capsules.
  • Driving impairment: warn patients not to drive until they have gained sufficient experience with Generic Neurontin Capsules to assess whether it will impair their ability to drive.
  • Somnolence/Sedation and Dizziness: Gabantin may impair the patient's ability to operate complex machinery (5.3) Increased seizure frequency may occur in patients with seizure disorders if Generic Neurontin Capsules (Gabantin)is abruptly discontinued
  • Suicidal Behavior and Ideation: monitor for suicidal thoughts and behavior
  • Neuropsychiatric Adverse Reactions in Children 3-12 Years of Age: monitor for such events

Side Effects of Generic Neurontin (Gabantin Capsules)

The common possible side effects reported in patients treated with Generic Neurontin (Gabantin Capsules) in adults, were dizzines, somnolence, and peripheral edema.

More Details

For more details on Generic Neurontin please read the Prescription Information or watch the presentation below.