Tuesday 4 November 2014

Hormone Replacement Therapy Using Generic Ovestin Cream

Generic Ovestin Cream (Evalon Vaginal Cream) – Product Information

Generic Ovestin Cream (Evalon Vaginal Cream) is used in Hormone Replacement Therapy (HRT) in women. It contains oestriol. Oestriol is one of the female hormones, called oestrogens, that is naturally produced in women. During and after the change of life (menopause) the oestrogen production decreases. This decrease may lead to hot flushes, vaginal irritation, recurrent urinary tract infections and urinary incontinence. Ovestin Cream can be prescribed for the loss of oestrogen production.
The active ingredient present in Generic Ovestin Cream is Estriol (Oestriol). Estriol (Oestriol) is particularly effective in the treatment of urogenital symptoms. In case of atrophy of the lower urogenital tract oestriol induces the normalization of the urogenital epithelium and helps to restore the normal microflora and the physiological pH in the vagina.

Dosage And Administration

Generic Ovestin Cream comes as a cream containing 1 mg Estriol for every 1 gm of the cream. The recommended dosage of Generic Ovestin Cream for adults is given below:

Atrophy of the Lower Urogenital Tract:
1 application (0.5g Generic Ovestin Cream) per day for the first weeks, followed by a gradual reduction, based on relief of symptoms, until a maintenance dosage (e.g. 1 application twice a week) is reached.

Pre- and Post-Operative Therapy in Postmenopausal Women Undergoing Vaginal Surgery:
1 application (0.5g Generic Ovestin Cream) per day in the 2 weeks before surgery; 1 application twice a week in the 2 weeks after surgery.

A Diagnostic Aid in case of a Doubtful Atrophic Cervical Smear:
1 application (0.5g Generic Ovestin Cream) on alternate days in the week before taking the next smear.

Generic Ovestin Cream (Evalon Vaginal Cream) - Contraindications

Generic Ovestin Cream (Evalon Vaginal Cream) is contraindicated for patients with hypersensitivity to Estriol or any of the inactive ingredients present in Generic Ovestin cream .
It is also contraindicated in the following cases:

  • you have had angina or a heart attack (myocardial infarction)
  • you have had a blood clot (thrombosis)
  • you have had breast cancer or suspect that you have breast cancer or you have had cancer of other sex organs such as cancer of the womb lining or ovary
  • you have vaginal bleeding that has not been explained by your doctor
  • you have excessive thickening of the womb lining
  • you have had a liver disease, and your liver is still not working properly
  • you have a rare blood problem called 'porphyria'

Generic Ovestin Cream - Warnings and Precautions

In case Generic Ovestin Cream (Evalon Vaginal Cream) is used for the treatment of postmenopausal symptoms, HRT should only be initiated for symptoms that adversely affect quality of life.
In all cases, a careful appraisal of the risks and benefits should be undertaken at least annually and HRT should only be continued as long as the benefit outweighs the risk.

Side Effects of Generic Ovestin Cream (Evalon Vaginal Cream)

The common side effects reported in patients treated with Generic Ovestin Cream (Evalon Vaginal Cream) include nausea and vomiting, breast tenderness or pain in the breasts, vaginal bleeding or spotting during or on withdrawal of therapy, excessive production of cervical mucous, headache, application site irritation and pruritus.

More Details about Generic Ovestin Cream

For more details on Generic Ovestin Cream please read the Prescription Information or watch see the presentation below.