Generic Anafranil (Clomipramine Hydrochloride Tablets)– Product Information
Generic Anafranil (Clomipramine Hydrochloride tablets) is used for the treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD). It is also used for the treatment of depressive states in adults including Major depressive disorder (MDD), Panic disorder with or without agoraphobia, Phobias and panic attacks, Body Dysmorphic Disorder, Depersonalization disorder, Trichotillomania, Cataplexy accompanying narcolepsy and Chronic painful conditions with or without organic disease.
The active ingredient present in Generic Anafranil (Clonil) is Clomipramine Hydrochloride.
Dosage And Administration
Clonil (Generic Anafranil) comes as an oral tablet in 10 mg, 25 mg and 50 mg dosage forms. The recommended Oral dosage of Generic Anafranil for adults is given below:
Treatment of Depression in Adults:
Clomipramine HCl (Clonil Tablets) therapy should be started at daily doses of 25 mg. Dosage may be increased by 25 mg increments, as tolerated, at 3 to 4 day intervals up to a total daily dose of 150 mg by the end of 2 weeks. Thereafter, the dose may be gradually increased over a period of several weeks to a maximum of 200 mg.
Treatment of Obsessive Compulsive Disorders in Adults:
Clomipramine HCl (Clonil Tablets) therapy in adult Obsessive Compulsive patients should be initiated at daily doses of 25 mg. Dosage may be increased by 25 mg increments, as tolerated, at 3 to 4 day intervals up to a total daily dose of 100 or 150 mg by the end of 2 weeks. Thereafter, the dose may be gradually increased over a period of several weeks to a maximum of 200 mg.
Clonil (Generic Anafranil) - Contraindications
Generic Anafranil (Clonil tablets) is contraindicated for patients with hypersensitivity to Clomipramine Hydrochloride or any of the inactive ingredients present in Clonil tablets.
Generic Anafranil Tablets - Warnings and Precautions
The risk of suicide is inherent in depression and may persist until significant remission occurs. This risk must be considered in all depressed patients.
Patients with depression may experience worsening of their depressive symptoms and/or the emergence of suicidal ideation and behaviours (suicidality) whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs.
When undergoing treatment with Generic Anafranil caution is required in patients with the following medical conditions:
- Cardiovascular disorders, especially those with cardiovascular insufficiency, conduction disorders or arrhythmias
- A history of increased intraocular pressure, narrow-angle glaucoma.
- Disorders of micturition due to an impeded flow of urine (e.g. in diseases of the prostate).
- A low convulsion threshold
- Severe hepatic or renal diseases.
- Tumours of the adrenal medulla in whom the medicine may provoke hypertensive crises.
- Hyperthyroidism or concomitant treatment with thyroid preparations.
- Chronic constipation, as tricyclic antidepressants may cause paralytic ileus, particularly in elderly and in bedridden patients.
Side Effects of Generic Anafranil Tablets
The common possible side effects of Generic Anafranil (Clonil tablets) with a frequency rate of 10% or more include:
- Accommodation disorder
- Blurred vision
- Nausea
- Dry mouth
- Constipation
- Fatigue
- Weight gain
- Increased appetite
- Dizziness
- Tremor
- Headache
- Myoclonus
- Drowsiness
- Somnolence
- Restlessness
- Vomiting
- Diarrhea
- Nervousness
- Stuffy nose
- Change in appetite or weight
- Decreased memory or concentration
- Decreased sexual ability
- Micturition disorder
- Sexual dysfunction (erectile dysfunction and loss of libido)
- Hyperhidrosis (profuse sweating)
- Uncontrollable shaking of a part of the body
- Seizures
- Fast, irregular, or pounding heartbeat
- Difficulty urinating or loss of bladder control
- Believing things that are not true
- Hallucinations (seeing things or hearing voices that do not exist)
- Eye pain
- Shakiness
- Difficulty breathing or fast breathing
- Severe muscle stiffness
- Unusual tiredness or weakness
- Sore throat, fever, and other signs of infection
More Details on Clomipramine Hydrochloride Tablets (Generic Anafranil)
For more details on Generic Anafranil (Clomipramine Hydrochloride tablets) please read the Prescription Information or watch the presentation below.
