Treatment of Asthma and COPD using Generic Symbicort Inhaler

Generic Symbicort (Foracort Inhaler) – Product Information

Generic Symbicort (Foracort Inhaler, manufactured by Cipla) is a combination of two medicines Formoterol Fumarate and Budesonide.
Budesonide is a glucocorticoid steroid that reduces inflammation. Formoterol Fumarate is a bronchodilator that relaxes muscles in the airways of the lungs to improve breathing. Generic Symbicort Inhaler is used treat asthma in patients 12 years of age and older. It is also used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema

Generic Symbicort (Foracort Inhaler) - Contraindications

Generic Symbicort (Foracort Inhaler) is contraindicated in patients with a hypersensitivity to Formoterol Fumarate, Budesonide or any inactive ingredient present in Foracort Inhaler. It is also contraindicated for primary treatment of status asthmaticus or acute episodes of asthma or COPD requiring intensive measures.

Generic Symbicort (Foracort Inhaler) - Dosage

Foracort Inhaler comes as an inhaler in 100mcg, 200mcg and 400mcg dosage forms. Each dose of Foracort 100 Inhaler delivers Formoterol Fumarate 6mcg and Budesonide 100 mcg, Foracort 200 Inhaler delivers Formoterol Fumarate 6 mcg and Budesonide 200 mcg, Foracort 400 Inhaler delivers Formoterol Fumarate 6 mcg and Budesonide 400 mcg. The recommended adult Oral dosage of Generic for adults is given below:
For Asthma:
The recommended dosage for patients 18 years and older is 1-2 inhalations of Foracort 100 (Formoterol Fumarate 6mcg + Budesonide 100 mcg) twice daily with a maximum of 4 inhalations twice daily.

Generic Symbicort (Foracort Inhaler) - Warnings and Precautions

The following precautions are to be observed when undergoing treatment using Generic Symbicort inhaler:

• Treatment with Foracort inhaler should not be initiated to treat a severe exacerbation or if patients have significantly worsening or acutely deteriorating asthma.
• The lowest effective dose of Generic Symbicort inhaler should be used.
• Patients should be reminded to take their Foracort maintenance dose as prescribed, even when asymptomatic.
• Once asthma symptoms are controlled, consideration may be given to stepping down treatment with Generic Symbicort inhaler.
• When long-term treatment with Generic Symbicort inhaler is to be discontinued, the dose should be tapered.

Side Effects of Generic Symbicort (Foracort Inhaler)

The possible side effects reported in patients treated with Generic Symbicort inhaler are listed below:
Common:
Palpitations, candida infection in the oropharynx, headache, tremor, mild irritation in the throat, coughing, hoarseness.
Uncommon:
Tachycardia, nausea, bruises, muscle cramps, dizziness, agitation, restlessness, nervousness, sleep disturbances.
Rare:
Cardiac arrhythmias, e.g. atrial fibrillation, supraventricular tachycardia, extrasystoles. Immediate and delayed hypersensitivity reactions, e.g. dermatitis, exanthema, urticaria, pruritus and angioedema. Bronchospasm, hypokalaemia.
Very rare:
Angina pectoris, signs and symptoms of systemic glucocorticosteroid effects, e.g. hypofunction of the adrenal gland, growth retardation, decrease in bone mineral density. Hyperglycaemia, depression, behavioural disturbances, taste disturbances, cataract, glaucoma.

Generic Symbicort (Foracort Inhaler) - More Details

For more details please read the Prescription Information or watch the presentation below:

Generic Symbicort Inhaler for Treatment of Asthma & COPD

Treatment of Cancer, Autoimmune diseases and Lymphoma using Generic Rheumatrex

What are Autoimmune Diseases?

Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. Your body's immune system protects you from disease and infection. But in case of patients with an autoimmune disease, the immune system can't tell the difference between healthy body tissue and antigens and consequently the immune system attacks healthy cells in the body.
The treatment of autoimmune diseases is typically with immunosuppression-medication that decreases the immune response.

Generic Rheumatrex (Neotrexate Tablets) – Product Information

Generic Rheumatrex (Neotrexate Tablets), an antimetabolite and antifolate drug. is used in treatment of cancer, neoplastic diseases, severe psoriasis (a skin disease which is characterised by red, scaly patches on some areas of the body), autoimmune diseases, ectopic pregnancy, Eczema, Lymphoma, Trophoblastic Disease and adult rheumatoid arthritis (Disease in which the body attacks its own joints).
The active ingredient present in Generic Rheumatrex is Methotrexate.
Methotrexate is available as Neotrexate, Rheumatrex, Trexall, MTX, Amethopterin and generic Methotrexate. Neotrexate Tablets (Generic Rheumatrex) are manufactued by GlaxoSmithKline India

Generic Rheumatrex (Neotrexate Tablets) - Contraindications

Generic Rheumatrex (Neotrexate Tablets) is contraindicated in patients with a known hypersensitivity to Methotrexate or to any component of this medication. It is also contraindicated in pregnant women and nursing mothers.
Methotrexate (Neotrexate Tablets) is also contraindicated in patients with alcoholism, alcoholic liver disease or other chronic liver disease those who have overt or laboratory evidence of immunodeficiency syndromes as well as those who have preexisting blood dyscrasias, such as bone marrow hypoplasia, leukopenia, thrombocytopenia or significant anemia.

Generic Rheumatrex (Neotrexate Tablets) - Dosage

The dosage of Generic Rheumatrex (Neotrexate Tablets) is different for different diseases and treatments. The adult dosage for some indications is given below:
Choriocarcinoma and similar trophoblastic diseases:
Methotrexate is administered orally in doses of 15 to 30 mg daily for a five-day course. Such courses are usually repeated for 3 to 5 times as required, with rest periods of one or more weeks interposed between courses, until any manifesting toxic symptoms subside.
Adult Rheumatoid Arthritis:
Recommended Starting Dosage Schedules
1. Single oral doses of 7.5 mg once weekly.
2. Divided oral dosages of 2.5 mg at 12 hour intervals for 3 doses given as a course once weekly
Polyarticular-Course Juvenile Rheumatoid Arthritis:
The recommended starting dose is 10 mg/m2 given once weekly

Side Effects of Generic Rheumatrex Tablets (Methotrexate)

The most common side effects of Generic Rheumatrex Tablets (Methotrexate) include ulcerative stomatitis, leukopenia, nausea, and abdominal distress. Other commonly reported side effects are malaise, undue fatigue, chills and fever, dizziness and decreased resistance to infection.

Generic Rheumatrex (Neotrexate Tablets) - More Details

For more details please read the Prescription Information or watch the presentation below:

Generic Rheumatrex Tablets for Treatment of Cancer and Neoplastic diseases

Treatment of Obsessions and Compulsions Using Generic Anafranil Tablets

Generic Anafranil (Clomipramine Hydrochloride Tablets)– Product Information

Generic Anafranil (Clomipramine Hydrochloride tablets) is used for the treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD). It is also used for the treatment of depressive states in adults including Major depressive disorder (MDD), Panic disorder with or without agoraphobia, Phobias and panic attacks, Body Dysmorphic Disorder, Depersonalization disorder, Trichotillomania, Cataplexy accompanying narcolepsy and Chronic painful conditions with or without organic disease.
The active ingredient present in Generic Anafranil (Clonil) is Clomipramine Hydrochloride.

Dosage And Administration

Clonil (Generic Anafranil) comes as an oral tablet in 10 mg, 25 mg and 50 mg dosage forms. The recommended Oral dosage of Generic Anafranil for adults is given below:
Treatment of Depression in Adults:
Clomipramine HCl (Clonil Tablets) therapy should be started at daily doses of 25 mg. Dosage may be increased by 25 mg increments, as tolerated, at 3 to 4 day intervals up to a total daily dose of 150 mg by the end of 2 weeks. Thereafter, the dose may be gradually increased over a period of several weeks to a maximum of 200 mg.
Treatment of Obsessive Compulsive Disorders in Adults:
Clomipramine HCl (Clonil Tablets) therapy in adult Obsessive Compulsive patients should be initiated at daily doses of 25 mg. Dosage may be increased by 25 mg increments, as tolerated, at 3 to 4 day intervals up to a total daily dose of 100 or 150 mg by the end of 2 weeks. Thereafter, the dose may be gradually increased over a period of several weeks to a maximum of 200 mg.

Clonil (Generic Anafranil) - Contraindications

Generic Anafranil (Clonil tablets) is contraindicated for patients with hypersensitivity to Clomipramine Hydrochloride or any of the inactive ingredients present in Clonil tablets.

Generic Anafranil Tablets - Warnings and Precautions

The risk of suicide is inherent in depression and may persist until significant remission occurs. This risk must be considered in all depressed patients.
Patients with depression may experience worsening of their depressive symptoms and/or the emergence of suicidal ideation and behaviours (suicidality) whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs.
When undergoing treatment with Generic Anafranil caution is required in patients with the following medical conditions:

• Cardiovascular disorders, especially those with cardiovascular insufficiency, conduction disorders or arrhythmias
• A history of increased intraocular pressure, narrow-angle glaucoma.
• Disorders of micturition due to an impeded flow of urine (e.g. in diseases of the prostate).
• A low convulsion threshold
• Severe hepatic or renal diseases.
• Tumours of the adrenal medulla in whom the medicine may provoke hypertensive crises.
• Hyperthyroidism or concomitant treatment with thyroid preparations.
• Chronic constipation, as tricyclic antidepressants may cause paralytic ileus, particularly in elderly and in bedridden patients.

Side Effects of Generic Anafranil Tablets

The common possible side effects of Generic Anafranil (Clonil tablets) with a frequency rate of 10% or more include:

• Accommodation disorder
• Blurred vision
• Nausea
• Dry mouth
• Constipation
• Fatigue
• Weight gain
• Increased appetite
• Dizziness
• Tremor
• Headache
• Myoclonus
• Drowsiness
• Somnolence
• Restlessness
• Vomiting
• Diarrhea
• Nervousness
• Stuffy nose
• Change in appetite or weight
• Decreased memory or concentration
• Decreased sexual ability
• Micturition disorder
• Sexual dysfunction (erectile dysfunction and loss of libido)
• Hyperhidrosis (profuse sweating)

Some side effects of Generic Anafranil tablets may be serious. If you experience any of the following symptoms listed below, call your doctor immediately or get emergency medical treatment:

• Uncontrollable shaking of a part of the body
• Seizures
• Fast, irregular, or pounding heartbeat
• Difficulty urinating or loss of bladder control
• Believing things that are not true
• Hallucinations (seeing things or hearing voices that do not exist)
• Eye pain
• Shakiness
• Difficulty breathing or fast breathing
• Severe muscle stiffness
• Unusual tiredness or weakness
• Sore throat, fever, and other signs of infection

More Details on Clomipramine Hydrochloride Tablets (Generic Anafranil)

For more details on Generic Anafranil (Clomipramine Hydrochloride tablets) please read the Prescription Information or watch the presentation below.

Clomipramine Hydrochloride for Treatment of Depression & Obsessive Compulsive Disorder (OCD)

Treatment of Arthritis, Bursitis and Tendinitis with Generic Indocin Capsules

What is Arthritis?

Arthritis is a degenerative joint disease, that involves inflammation of one or more joints. There are over 100 different types of arthritis. The most common form, osteoarthritis involves the breakdown of cartilage. The breakdown of cartilage can take place as as a result of trauma to the joint, infection of the joint, or age. This causes causes the bones to rub against each other, causing stiffness, swelling (inflammation), pain and loss of movement in the joint. Other forms of arthritis include rheumatoid arthritis, psoriatic arthritis, and related autoimmune diseases. Septic arthritis is caused by joint infection. The main complaint among individuals who suffer from arthritis is joint pain. The pain is usually localized to the joint affected and is due to inflammation that occurs around the joint, damage to the joint from disease, daily wear and tear of joint, muscle strains caused by forceful movements against stiff, painful joints and fatigue.

What is Tendinitis and Bursitis?

Tendinitis or bursitis often involves the shoulder, elbow, wrist, hip, knee and ankle. The pain caused by Bursitis and Tendinitis could be quite severe and is worse during movement.
What is tendinitis?
Tendons are cord-like structures located where a muscle narrows down to attach to a bone. The tendon is more fibrous and dense than the elastic, fleshy muscle. A tendon transmits the pull of the muscle to the bone to cause movement. Tendinitis (informally also tendonitis), means the inflammation of a tendon. Tendinitis is often very tender to the touch. The term tendinitis is reserved for tendon injuries that involve larger-scale acute injuries accompanied by inflammation. Generally tendinitis is referred to by the body part involved, such as Achilles tendinitis (affecting the Achilles tendon), or patellar tendinitis (jumper's knee, affecting the patellar tendon).
What is bursitis?
Bursitis is the inflammation of one or more bursae (small sacs) of synovial fluid in the body. The bursae rest at the points where internal functionaries, such as muscles and tendons, slide across bone. This small sac acts as a cushion between moving structures (bones, muscles, tendons or skin). Healthy bursae create a smooth, almost frictionless functional gliding surface making normal movement painless. If a muscle or tendon is pulling around a corner of a bone, or over a bone, a healthy bursa protects it from fraying and stress.
When bursitis occurs and a bursa is inflamed, movement relying upon the inflamed bursa becomes difficult and painful. Moreover, movement of tendons and muscles over the inflamed bursa aggravates its inflammation, perpetuating the problem. Muscle can also be stiffened.
Tendinitis can occur from a sudden intense injury. Most often, though, it results from a repeated, minor injury of that tendon. Doctors call this repetitive stress or overuse. Examples of such injuries are painting a ceiling for four hours or more, typing long hours, improper body position while using a keyboard, chopping, cutting or sawing may result in tendinitis or bursitis hours or days later. Tight clenching while using hand tools or while driving a long time, using a backhand, mainly single handed, in an early-season game of tennis ("tennis elbow") and wearing improper running shoes or not getting the proper training before sports are other examples.

Generic Indocin Capsules (Inmecin) – Product Information

Generic Indocin Capsules (Inmecin Capsules) is used to relieve moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
The active ingredient present in Generic Indocin Capsules is Indomethacin.
Indomethacin is marketed under trade names such as Inmecin,Indocid, Indocid Pda, Indocid Sr, Indocin, Rheumacin, Indocap, Indochron and several others.

Generic Indocin Capsules (Inmecin Capsules) - Contraindications

Generic Indocin Capsules (Inmecin Capsules) is contraindicated in patients with known hypersensitivity to indomethacin or any inactive ingredient present in Generic Indocin Capsules.
Inmecin Capsules (Generic Indocin) should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic/anaphylactoid reactions to NSAIDs have been reported in such patients. Indomethacin (Generic Indocin) is also contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.

Generic Indocin (Inmecin Capsules) - Dosage

The recommended adult Oral dosage of Generic Indocin(Inmecin Capsules) for adults is given below:
Moderate To Severe Rheumatoid Arthritis Including Acute Flares Of Chronic Disease, Moderate To Severe Ankylosing Spondylitis, And Moderate To Severe Osteoarthritis
Recommended Adult Dosage: Indomethacin capsules 25 mg twice a day or three times a day If this is well tolerated, increase the daily dosage by 25 or by 50 mg, if required by continuing symptoms, at weekly intervals until a satisfactory response is obtained or until a total daily dose of 150 to 200 mg is reached.
Acute Painful Shoulder (Bursitis And/Or Tendinitis)
The initial adult doseage is 75 to 150 mg daily in 3 or 4 divided doses. Generic Indocin (Inmecin capsules) should be discontinued after the signs and symptoms of inflammation have been controlled for several days. The usual course of therapy is 7 to 14 days.
Acute Gouty Arthritis
The adult dosage is 50 mg of Generic Indocin capsules thrice a day until pain is tolerable. The dose should then be rapidly reduced to complete cessation of the drug. Definite relief of pain has been reported within 2 to 4 hours. Tenderness and heat usually subside in 24 to 36 hours, and swelling gradually disappears in 3 to 5 days.

Side Effects of Generic Indocin Capsules (Indomethacin)

The most common side effects reported in patients treated with Generic Indocin are headache, dizziness, light-headedness, changes in mood including depression, tiredness, spinning sensation (vertigo), stomach upset including nausea (feeling sick), vomiting, abdominal pain, loss of appetite, constipation, diarrhoea, ringing ears or other hearing disturbances flushing, and sweating.
The rare but serious side effects of Indomethacin include severe stomach pain or tenderness, eye problems including blurred vision, irregular heart beat, bleeding or bruising more frequently, jaundice (symptoms include yellowing of the skin and eyes), hepatitis, rash, itchy skin, loss of hair, unusual weight gain, swelling of ankles or legs, signs of anaemia such as tiredness, being short of breath, looking pale, changes in the frequency that you urinate or difficulty passing urine, dark coloured or cloudy urine.

Generic Indocin Capsules - More Details

For more details on please read the Prescription Information or watch the presentation below:

Generic Indocin Capsules for Treatment of Arthritis, Bursitis and Tendinitis